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Titolo:
LEPTIN
Autore:
AUWERX J; STAELS B;
Indirizzi:
INST PASTEUR,INSERM,DEPT ATHEROSCLEROSE,LAB BIOL REGULAT EUCARYOTES,1RUE CALMETTE F-59019 LILLE FRANCE
Titolo Testata:
Lancet
fascicolo: 9104, volume: 351, anno: 1998,
pagine: 737 - 742
SICI:
0140-6736(1998)351:9104<737:>2.0.ZU;2-V
Fonte:
ISI
Lingua:
ENG
Soggetto:
OB GENE-EXPRESSION; ACTIVATED RECEPTOR-GAMMA; WHITE ADIPOSE-TISSUE; MOUSE OBESE GENE; NEUROPEPTIDE-Y; BODY-WEIGHT; FOOD-INTAKE; OB/OB MICE; DB/DB MICE; TRANSCRIPTION FACTOR;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
96
Recensione:
Indirizzi per estratti:
Citazione:
J. Auwerx e B. Staels, "LEPTIN", Lancet, 351(9104), 1998, pp. 737-742

Abstract

Leptin (from the Greek leptos=thin) was identified only 3 years ago. It has attracted huge attention both scentifically, with more than 600publications, and in the media, where this protein has been portrayedas the way to a cure for obesity. Indeed, leptin was first described as an adipocyte-derived signalling factor, which, after interaction with its receptors, induced a complex response including control of bodyweight and energy expenditure. Leptin seems in addition to its role inmetabolic control to have important roles In reproduction and neuroendocrine signalling. Human obesity is a complex disorder, with many factors playing a part; the pathophysiology of leptin is not as simple asit seems to be in rodent models of obesity.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 29/03/20 alle ore 18:21:13