Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
DECOUPLING THEORY AND PRACTICE II - STATE-OF-THE-ART - IN-VIVO APPLICATIONS OF DECOUPLING
Autore:
FREEMAN DM; HURD R;
Indirizzi:
HEWLETT PACKARD LABS PALO ALTO CA 94304 GE CO,MED SYST FREMONT CA 00000
Titolo Testata:
NMR in biomedicine
fascicolo: 8, volume: 10, anno: 1997,
pagine: 381 - 393
SICI:
0952-3480(1997)10:8<381:DTAPI->2.0.ZU;2-Q
Fonte:
ISI
Lingua:
ENG
Soggetto:
COHERENCE-TRANSFER NMR; HUMAN-CALF-MUSCLE; IN-VIVO; MAGNETIC-RESONANCE; NORMAL VOLUNTEERS; RAT-BRAIN; C-13 NMR; SPECTROSCOPY; ENHANCEMENTS; TISSUE;
Keywords:
DECOUPLING; SENSITIVITY; RESOLUTION ENHANCEMENT; POWER DEPOSITION; BIOLOGICAL TISSUE; RADIOFREQUENCY HEATING;
Tipo documento:
Article
Natura:
Periodico
Citazioni:
39
Recensione:
Indirizzi per estratti:
Citazione:
D.M. Freeman e R. Hurd, "DECOUPLING THEORY AND PRACTICE II - STATE-OF-THE-ART - IN-VIVO APPLICATIONS OF DECOUPLING", NMR in biomedicine, 10(8), 1997, pp. 381-393

Abstract

Current methods for broadband heteronuclear decoupling are reviewed from a historical perspective, The principal concern is that decouplingshould be effective over a wide range of chemical shifts without undue radiofrequency heating of the sample, particularly when human patients are involved, continuous-wave methods are the least efficient in this respect, followed by noise decoupling, Composite pulse schemes offer a more effective use of radiofrequency power, while adiabatic passage methods are the most efficient of all, Bi-level decoupling employs alow level of radiofrequency irradiation during the relaxation delay to maintain the nuclear Overhauser effect, with a higher level during signal acquisition in order to decouple over a wide frequency band, Alldecoupling sequences introduce cycling sidebands into the observed spectrum, and schemes are described to minimize the intensity of these artifacts, In part II, practical applications of decoupling methods areexamined in the context of in vivo spectroscopy, where the improvements in sensitivity and resolution through broadband decoupling can be critical for solving clinical problems, Attention is focused on the regulatory limits on power deposition in these experiments. A tabulation of the existing work on decoupling in biological tissue is presented,mainly involving P-31 and C-13 spectroscopy in vivo or in vitro. (C) 1997 John Wiley & Sons, Ltd.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 09/07/20 alle ore 17:19:59