Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
HEPATIC VENULAR RESISTANCE RESPONSES TO NOREPINEPHRINE, ISOPROTERENOL, ADENOSINE, HISTAMINE, AND ACH IN RABBITS
Autore:
ROTHE CF; MAASSMORENO R;
Indirizzi:
INDIANA UNIV,SCH MED,DEPT PHYSIOL,MED SCI RM 374,635 BARNHILL DR INDIANAPOLIS IN 46202 INDIANA UNIV,SCH MED,DEPT PHYSIOL & BIOPHYS INDIANAPOLIS IN 46202
Titolo Testata:
American journal of physiology. Heart and circulatory physiology
fascicolo: 3, volume: 43, anno: 1998,
pagine: 777 - 785
SICI:
0363-6135(1998)43:3<777:HVRRTN>2.0.ZU;2-M
Fonte:
ISI
Lingua:
ENG
Soggetto:
VASCULAR CAPACITANCE; BLOOD-FLOW; VENOUS COMPLIANCE; LIVER; SYSTEM; VOLUME; DOGS; RAT; MICROCIRCULATION; STIMULATION;
Keywords:
HEPATIC VENOUS RESISTANCE; LIVER; MICROCIRCULATION; VENOCONSTRICTION;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
40
Recensione:
Indirizzi per estratti:
Citazione:
C.F. Rothe e R. Maassmoreno, "HEPATIC VENULAR RESISTANCE RESPONSES TO NOREPINEPHRINE, ISOPROTERENOL, ADENOSINE, HISTAMINE, AND ACH IN RABBITS", American journal of physiology. Heart and circulatory physiology, 43(3), 1998, pp. 777-785

Abstract

Changes in hepatic venous resistance were estimated in rabbits from the hepatic venular-inferior vena caval pressure gradient [servo-null micropipettes in 49 +/- 15 (SD) mu m vessels] and the total hepatic blood flow (ultrasound probe encircling the hepatic artery and the portalvein). Changes in liver volume, and thus vascular capacitance, were estimated from measures of the liver lobe thickness. Norepinephrine (NE), isoproterenol (Iso), adenosine (Ado), histamine (Hist), or acetylcholine (ACh) was infused into the portal vein at a constant rate for 5 min. NE, Hist, and Ado increased hepatic venular pressure, but only NEand Hist significantly increased hepatic venular resistance. NE reduced the liver thickness, but Hist and Ado caused engorgement. Hepatic blood flow was increased by NE and Ado and decreased by ACh. The influence of intraportal vein infusion of Iso on the liver vasculature, at doses similar to that of NE, was insignificant. We conclude that NE acted on all the hepatic microvasculature, increasing resistance and actively decreasing vascular volume. Hist passively induced engorgement byincreasing outflow resistance, whereas the liver engorgement seen with Ado was passively related to the increased blood flow. ACh constricted the portal venules but did not change the liver volume.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 04/12/20 alle ore 19:57:17