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Titolo:
VISCERAL ORTHOSTATIC HYPOTENSION IN PATIENTS WITH SEVERE AUTONOMIC DYSFUNCTION
Autore:
TERAZAKI H; ANDO Y; YAMASHITA T; OBAYASHI K; NAKAMURA K; NAKAMURA M; YOSHIMATSU S; SUGA M; UCHINO M; ANDO M;
Indirizzi:
UMEA UNIV HOSP,DEPT MED S-90185 UMEA SWEDEN KUMAMOTO UNIV,SCH MED,DEPT INTERNAL MED 1 KUMAMOTO 860 JAPAN KUMAMOTO UNIV,SCH MED,DEPT NEUROL KUMAMOTO 860 JAPAN
Titolo Testata:
Journal of the autonomic nervous system
fascicolo: 1-2, volume: 68, anno: 1998,
pagine: 101 - 108
SICI:
0165-1838(1998)68:1-2<101:VOHIPW>2.0.ZU;2-#
Fonte:
ISI
Lingua:
ENG
Soggetto:
FAMILIAL AMYLOIDOTIC POLYNEUROPATHY; ARTERY BLOOD-FLOW; TRANSCRANIAL DOPPLER; PORTAL-HYPERTENSION; DUPLEX-DOPPLER; JAPANESE TYPE; FLOWMETRY; RESPONSES; DIAGNOSIS; DISEASE;
Keywords:
FAMILIAL AMYLOIDOTIC POLYNEUROPATHY; ORTHOSTATIC HYPOTENSION; DOPPLER ULTRASONOGRAPHY; AUTONOMIC DYSFUNCTION; PORTAL VEIN;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
31
Recensione:
Indirizzi per estratti:
Citazione:
H. Terazaki et al., "VISCERAL ORTHOSTATIC HYPOTENSION IN PATIENTS WITH SEVERE AUTONOMIC DYSFUNCTION", Journal of the autonomic nervous system, 68(1-2), 1998, pp. 101-108

Abstract

Although changes in the blood flow of the cerebral vessels and the peripheral vessels in the extremities after changing body postures have been well examined in patients with orthostatic hypotension (OH), suchchanges in visceral vessels have not been well investigated. To elucidate the effect of autonomic dysfunctions on changes in the abdominal blood flow, the blood flow velocity of the portal vein was measured byDoppler ultrasonography in 11 patients with familial amyloidotic polyneuropathy (FAP) (Met30), 3 with pandysautonomia, 1 with Shy-Drager syndrome, and 10 healthy controls, in the supine and at the upright position. Among the 15 patients with the above-mentioned autonomic disorders, 5 of the patients showed a marked decrease in blood flow after standing, and one of these 5 patients exhibited transient hepatic and intestinal ischemia during intensive rehabilitation because of a severe decrease in visceral blood flow. Another 7 patients exhibited moderate decreases in the blood flow after standing. In contrast, no such change was observed in the 10 healthy controls. The FAP patients with L-threo-3,4-dihydroxyphenylserine (L-threo-DOPS) administration showed no significant correlation between the degree of OH and the decrease in the blood flow of the portal vein, and the patients without the drug exhibited a weak correlation. On the contrary, the pandysautonomia and Shy-Drager syndrome patients exhibited a linear positive correlation. These results suggest that FAP is a disease for which this kind of ultrasonographic examination should be applied, and that Doppler ultrasonography may be a helpful tool to evaluate visceral OH. (C) 1998 ElsevierScience B.V.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 07/08/20 alle ore 06:33:45