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Titolo:
THE SIGNIFICANCE OF VITAMIN-A AND CAROTENOID STATUS IN PERSONS INFECTED BY THE HUMAN-IMMUNODEFICIENCY-VIRUS
Autore:
NIMMAGADDA A; OBRIEN WA; GOETZ MB;
Indirizzi:
W LOS ANGELES VET AFFAIRS MED CTR,DEPT MED,111F,11301 WILSHIRE BLVD LOS ANGELES CA 90073 W LOS ANGELES VET AFFAIRS MED CTR,DEPT MED LOS ANGELES CA 90073 UNIV CALIF LOS ANGELES,SCH MED LOS ANGELES CA 90024
Titolo Testata:
Clinical infectious diseases
fascicolo: 3, volume: 26, anno: 1998,
pagine: 711 - 718
SICI:
1058-4838(1998)26:3<711:TSOVAC>2.0.ZU;2-5
Fonte:
ISI
Lingua:
ENG
Soggetto:
BETA-CAROTENE; A-DEFICIENCY; HIV-INFECTION; TYPE-1 INFECTION; DIETARY-INTAKE; MILD VITAMIN; CARDIOVASCULAR-DISEASE; MICRONUTRIENT INTAKE; RESPIRATORY-DISEASE; INCREASED MORTALITY;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
83
Recensione:
Indirizzi per estratti:
Citazione:
A. Nimmagadda et al., "THE SIGNIFICANCE OF VITAMIN-A AND CAROTENOID STATUS IN PERSONS INFECTED BY THE HUMAN-IMMUNODEFICIENCY-VIRUS", Clinical infectious diseases, 26(3), 1998, pp. 711-718

Abstract

Hyporetinemia is associated with increased childhood morbidity and mortality that is reversible with vitamin A supplementation. Although vitamin A deficiency is otherwise rare in developed countries, the prevalence of hyporetinemia in human immunodeficiency virus (HIV)-infected persons is up to 29%. Hyporetinemic HIV-infected patients have a 3.5-5-fold increased risk of death. Furthermore, HIV-infected patients withvery low or very high intake of vitamin A and beta-carotene (a vitamin A precursor) have greater rates of disease progression than do patients with intermediate intake. In developing countries up to 60% of HIV-infected pregnant women are hyporetinemic. In such women the relativerisk of perinatal HIV transmission may be increased more than fourfold. These data indicate that vitamin A deficiency is common in HIV-infected patients in the developed world and strongly suggest that vitaminA supplementation may be especially useful in adjunctive therapy for HIV-infected pregnant women who reside in the developing world.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 21/09/20 alle ore 06:31:09