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Titolo:
THE NEW-YORK HIGH-RISK PROJECT - ATTENTION, ANHEDONIA AND SOCIAL OUTCOME
Autore:
FREEDMAN LR; ROCK D; ROBERTS SA; CORNBLATT BA; ERLENMEYERKIMLING L;
Indirizzi:
NEW YORK STATE PSYCHIAT INST & HOSP,DEPT MED GENET,722 W 168TH ST NEWYORK NY 10032 COLUMBIA UNIV COLL PHYS & SURG,DEPT PSYCHIAT NEW YORK NY 10032 EDUC TESTING SERV PRINCETON NJ 08541 LONG ISL JEWISH MED CTR,DEPT PSYCHIAT GLEN OAKS NY 00000 COLUMBIA UNIV COLL PHYS & SURG,DEPT GENET & DEV NEW YORK NY 10032
Titolo Testata:
Schizophrenia research
fascicolo: 1, volume: 30, anno: 1998,
pagine: 1 - 9
SICI:
0920-9964(1998)30:1<1:TNHP-A>2.0.ZU;2-K
Fonte:
ISI
Lingua:
ENG
Soggetto:
PSYCHOSIS PRONENESS; PHYSICAL ANHEDONIA; SCHIZOPHRENIA; SCALES; PSYCHOPATHOLOGY; PERSONALITY; COMPETENCE; SCHIZOTYPY; DISORDERS; DEVIANCE;
Keywords:
GENETICS; SCHIZOPHRENIA; HIGH-RISK; ATTENTION DEVIANCE; PHYSICAL ANHEDONIA; SOCIAL OUTCOME;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Physical, Chemical & Earth Sciences
Science Citation Index Expanded
Citazioni:
42
Recensione:
Indirizzi per estratti:
Citazione:
L.R. Freedman et al., "THE NEW-YORK HIGH-RISK PROJECT - ATTENTION, ANHEDONIA AND SOCIAL OUTCOME", Schizophrenia research, 30(1), 1998, pp. 1-9

Abstract

In the New York High-Risk Project we have followed two samples of subjects (Sample A and Sample B) at risk for schizophrenic or affective disorders and low-risk controls from childhood to adulthood, in an attempt to identify early predictors of later psychopathology. We administered a large number of cognitive, psychometric and other types of measures to both samples as possible psychopathology predictors, includingan index of attentional deviance assessed in childhood, the Physical Anhedonia Scale in adolescence, and three measures of social outcome in adulthood ('Suspicious Solitude', 'Social Insecurity', and 'Lack of Empathy'), derived from the Personality Disorders Examination. In the analysis of the combined samples, parental diagnostic group, gender, attentional deviance in childhood, and physical anhedonia in adolescence were used to predict three measures of social outcome in adulthood. While only physical anhedonia was directly related to all three socialoutcome measures, with the strongest relationship to Suspicious Solitude, attention deviance successfully predicted two of the three outcomes. Subjects at risk for affective disorder did not show increased levels of attention deviance, physical anhedonia, or social dysfunction, relative to the normal control subjects. Attention deviance appears tobe a key neurobiological indicator and physical anhedonia appears to be a potentiating factor mediating the relationship between risk for schizophrenia and later social dysfunction. (C) 1998 Elsevier Science B. V.

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Documento generato il 20/01/20 alle ore 16:10:15