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Titolo:
NUCLEAR AND CYTOPLASMIC DETERMINANTS INVOLVED IN THE REGULATION OF MAMMALIAN OOCYTE MATURATION
Autore:
FULKA J; FIRST NL; MOOR RM;
Indirizzi:
INST ANIM PROD CS-10401 PRAGUE 10 CZECH REPUBLIC BABRAHAM INST,DEPT GENET & DEV CAMBRIDGE CB2 4AT ENGLAND UNIV WISCONSIN,DEPT MEAT & ANIM SCI MADISON WI 53706
Titolo Testata:
Molecular human reproduction
fascicolo: 1, volume: 4, anno: 1998,
pagine: 41 - 49
SICI:
1360-9947(1998)4:1<41:NACDII>2.0.ZU;2-L
Fonte:
ISI
Lingua:
ENG
Soggetto:
CHROMOSOME CONDENSATION ACTIVITY; GERMINAL VESICLE BREAKDOWN; MOUSE OOCYTES; MEIOTIC MATURATION; CELL-CYCLE; PARTHENOGENETIC DEVELOPMENT; PROMOTING FACTOR; IN-VITRO; PORCINE OOCYTES; PIG OOCYTES;
Keywords:
CYTOPLASM; NUCLEUS; OOCYTE;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
73
Recensione:
Indirizzi per estratti:
Citazione:
J. Fulka et al., "NUCLEAR AND CYTOPLASMIC DETERMINANTS INVOLVED IN THE REGULATION OF MAMMALIAN OOCYTE MATURATION", Molecular human reproduction, 4(1), 1998, pp. 41-49

Abstract

The requisite endpoint of mammalian oocyte maturation, whether in vivo or in vitro,is a metaphase II oocyte which is able to be fertilized and which can eventually support normal embryonic development. Oocyteswhich have been matured in vivo basically fulfil these criteria. On the other hand, a completely different situation exists when these cells are isolated from the ovaries and cultured in vitro. If they are toosmall (growing oocytes), they do not undergo maturation, or, if more advanced, will mature only to the metaphase I stage. Even in fully grown oocytes which are able to mature to metaphase Il, the developmentalpotential after fertilization is disappointingly low, for reasons which remain unknown. The complexity of certain factors (nuclear, cytoplasmic or arising from our current culture systems) undoubtedly influences both the ability of oocytes to mature fully, as well as their developmental potential after fertilization.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 26/09/20 alle ore 04:14:50