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Titolo:
THIOPENTAL-ROCURONIUM VERSUS KETAMINE-ROCURONIUM FOR RAPID-SEQUENCE INTUBATION IN PARTURIENTS UNDERGOING CESAREAN-SECTION
Autore:
BARAKA AS; SAYYID SS; ASSAF BA;
Indirizzi:
AMER UNIV BEIRUT,DEPT ANESTHESIOL BEIRUT LEBANON
Titolo Testata:
Anesthesia and analgesia
fascicolo: 5, volume: 84, anno: 1997,
pagine: 1104 - 1107
SICI:
0003-2999(1997)84:5<1104:TVKFRI>2.0.ZU;2-8
Fonte:
ISI
Lingua:
ENG
Soggetto:
ADDUCTOR POLLICIS; NEUROMUSCULAR BLOCKADE; VECURONIUM; ANESTHESIA; INDUCTION; ORG-9426; MUSCLES; SUCCINYLCHOLINE; ALFENTANIL; PROPOFOL;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
17
Recensione:
Indirizzi per estratti:
Citazione:
A.S. Baraka et al., "THIOPENTAL-ROCURONIUM VERSUS KETAMINE-ROCURONIUM FOR RAPID-SEQUENCE INTUBATION IN PARTURIENTS UNDERGOING CESAREAN-SECTION", Anesthesia and analgesia, 84(5), 1997, pp. 1104-1107

Abstract

We investigated the neuromuscular effects and conditions of tracheal intubation after administration of rocuronium in 40 parturients undergoing elective cesarean section. After preoxygenation, anesthesia was induced in 20 patients by thiopental 4 mg/kg and, in the other 20 patients, by ketamine 1.5 mg/kg. Rocuronium 0.6 mg/kg was then administered, and neuromuscular transmission was assessed using electromyographic response to train-of-four stimulation of the ulnar nerve at the wrist every 10 s. The time to T1/control ratio of 50% neuromuscular block (NMB) as well as the time to maximum NMB (onset time) were compared in the two groups. The time to 50% block was 45 +/- 10 s in the thiopentalgroup and 42 +/- 14 s in the ketamine group, while the onset time was105 +/- 35 s in the thiopental group and 101 +/- 35 s in the ketaminegroup. Neither the time to 50% NMB nor the onset time were significantly different between the two groups. Tracheal intubation at 50% NMB was easily performed in all patients in the ketamine-rocuronium group but was difficult in 75% of the thiopental-rocuronium group. We concluded that ketamine 1.5 mg/kg followed by rocuronium 0.6 mg/kg may be suitable for rapid-sequence induction of anesthesia in parturients undergoing cesarean section.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 31/03/20 alle ore 05:10:05