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Titolo:
IMMUNOMODULATING THERAPEUTIC APPROACHES FOR MULTIPLE-SCLEROSIS
Autore:
KARUSSIS DM; ABRAMSKY O;
Indirizzi:
HADASSAH UNIV HOSP,DEPT NEUROL IL-91120 JERUSALEM ISRAEL
Titolo Testata:
Journal of the neurological sciences
fascicolo: 2, volume: 153, anno: 1998,
pagine: 239 - 250
SICI:
0022-510X(1998)153:2<239:ITAFM>2.0.ZU;2-L
Fonte:
ISI
Lingua:
ENG
Soggetto:
EXPERIMENTAL ALLERGIC ENCEPHALOMYELITIS; EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS; MYELIN BASIC-PROTEIN; T-CELL SUBSETS; INTERCELLULAR-ADHESION MOLECULE-1; CD45 ISOFORM EXPRESSION; CENTRAL-NERVOUS-SYSTEM; TRANSFORMING GROWTH FACTOR-BETA-1; PLACEBO-CONTROLLED TRIAL; ACUTE OPTIC NEURITIS;
Keywords:
MULTIPLE SCLEROSIS (MS); EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS (EAE); IMMUNOMODULATION;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
185
Recensione:
Indirizzi per estratti:
Citazione:
D.M. Karussis e O. Abramsky, "IMMUNOMODULATING THERAPEUTIC APPROACHES FOR MULTIPLE-SCLEROSIS", Journal of the neurological sciences, 153(2), 1998, pp. 239-250

Abstract

In this review we delineate the rationale for immunotherapy in multiple sclerosis and describe the various levels at which immune intervention, according to a modem model of the immune system organization, is feasible. Current and future immunosuppressive and immunomodulating therapeutic approaches at the level of antigen presentation and at the lymphocyte and cytokine network levels are discussed. (C) 1998 ElsevierScience B.V.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 21/09/20 alle ore 16:19:16