Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
THE EVOLUTIONARY HISTORY OF THE GENUS ACANTHAMOEBA AND THE IDENTIFICATION OF 8 NEW 18S RIBOSOMAL-RNA GENE SEQUENCE TYPES
Autore:
STOTHARD DR; SCHROEDERDIEDRICH JM; AWWAD MH; GAST RJ; LEDEE DR; RODRIGUEZZARAGOZA S; DEAN CL; FUERST PA; BYERS TJ;
Indirizzi:
OHIO STATE UNIV,DEPT MOL GENET,484 W 12TH AVE COLUMBUS OH 43210 OHIO STATE UNIV,DEPT MOL GENET COLUMBUS OH 43210
Titolo Testata:
The Journal of eukaryotic microbiology
fascicolo: 1, volume: 45, anno: 1998,
pagine: 45 - 54
SICI:
1066-5234(1998)45:1<45:TEHOTG>2.0.ZU;2-K
Fonte:
ISI
Lingua:
ENG
Soggetto:
SUBUNIT RIBOSOMAL-RNAS; MITOCHONDRIAL-DNA; PROTEIN SEQUENCES; N-SP; INFECTIONS; ISOENZYME; GRIFFINI; STRAINS;
Keywords:
CLASSIFICATION; GRANULOMATOUS AMEBIC ENCEPHALITIS; KERATITIS; MULTIPLE RDNA ALLELES; OPPORTUNISTIC PATHOGEN; PHYLOGENY;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
34
Recensione:
Indirizzi per estratti:
Citazione:
D.R. Stothard et al., "THE EVOLUTIONARY HISTORY OF THE GENUS ACANTHAMOEBA AND THE IDENTIFICATION OF 8 NEW 18S RIBOSOMAL-RNA GENE SEQUENCE TYPES", The Journal of eukaryotic microbiology, 45(1), 1998, pp. 45-54

Abstract

The 18S rRNA gene (Rns) phylogeny of Acanthamoeba is being investigated as a basis for improvements in the nomenclature and taxonomy of thegenus. We previously analyzed Rns sequences from 18 isolates from morphological groups 2 and 3 and found that they fell into four distinct evolutionary lineages we called sequence types T1-T4. Here, we analyzed sequences from 53 isolates representing 16 species and including 35 new strains. Eight additional lineages (sequence types T5-T12) were identified. Four of the 12 sequence types included strains from more than one nominal species. Thus, sequence types could be equated with species in some cases or with complexes of closely related species in others. The largest complex, sequence type T4, which contained six closelyrelated nominal species, included 24 of 25 keratitis isolates. Rns sequence variation was insufficient for full phylogenetic resolution of branching orders within this complex, but the mixing of species observed at terminal nodes confirmed that traditional classification of isolates has been inconsistent. One solution to this problem would be to equate sequence types and single species. Alternatively, additional molecular information will be required to reliably differentiate species within the complexes. Three sequence types of morphological group 1 species represented the earliest divergence in the history of the genus and, based on their genetic distinctiveness, are candidates for reclassification as one or more novel genera.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 13/07/20 alle ore 18:11:06