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Titolo:
CEREBROSPINAL-FLUID MARKERS IN MULTIPLE-SCLEROSIS - AN OVERVIEW
Autore:
MASSARO AR; TONALI P;
Indirizzi:
UNIV SACRED HEART,SCH MED,NEUROL INST I-00168 ROME ITALY
Titolo Testata:
Multiple sclerosis
fascicolo: 1, volume: 4, anno: 1998,
pagine: 1 - 4
SICI:
1352-4585(1998)4:1<1:CMIM-A>2.0.ZU;2-H
Fonte:
ISI
Lingua:
ENG
Soggetto:
INTERMEDIATE FILAMENT PROTEINS; MYELIN BASIC-PROTEIN; NERVE GROWTH-FACTOR; NEUROLOGICAL DISORDERS; CSF DIAGNOSTICS; S-100 PROTEIN; OLIGODENDROCYTES; TOOLS;
Keywords:
MULTIPLE SCLEROSIS; CEREBROSPINAL FLUID; BIOLOGICAL MARKERS; DEMYELINATION; REMYELINATION; MRI; S-100; N-CAM; CNTF;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
31
Recensione:
Indirizzi per estratti:
Citazione:
A.R. Massaro e P. Tonali, "CEREBROSPINAL-FLUID MARKERS IN MULTIPLE-SCLEROSIS - AN OVERVIEW", Multiple sclerosis, 4(1), 1998, pp. 1-4

Abstract

Cerebrospinal fluid (CSF), with its protein markers, is a formidable material for investigating the relationships among the various cell types involved during the initial phase of plaque formation, or, successively, in the remyelination process. Its analysis may give definite help in better focusing on therapeutic objectives and therapeutic tools. Therefore, the possible use of CSF MBP, S-100, GFAP, N-CAM, NGF, and CNTF in pathogenetic studies and in clinical follow-up is critically reviewed. The need for correct interpretation of the data, for uniformity and reliability of the analytical methods, and for easy access to them is stressed. CSF examination and MRI should not be considered as alternative tools, or in competition, but should be used together, to take the maximum advantage of their individual possibilities.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 24/01/20 alle ore 12:25:48