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Titolo:
HYPOTENSIVE EFFECT OF GAMMA-GLUTAMYLMETHYLAMIDE IN SPONTANEOUSLY HYPERTENSIVE RATS
Autore:
YOKOGOSHI H; KOBAYASHI M;
Indirizzi:
UNIV SHIZUOKA,SCH FOOD & NUTR SCI,LAB NUTR BIOCHEM,52-1 YADA SHIZUOKA422 JAPAN
Titolo Testata:
Life sciences
fascicolo: 12, volume: 62, anno: 1998,
pagine: 1065 - 1068
SICI:
0024-3205(1998)62:12<1065:HEOGIS>2.0.ZU;2-J
Fonte:
ISI
Lingua:
ENG
Soggetto:
BLOOD-PRESSURE;
Keywords:
GAMMA-GLUTAMYLMETHYLAMIDE; HYPOTENSION; BLOOD PRESSURE; SHR; GREEN TEA;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
12
Recensione:
Indirizzi per estratti:
Citazione:
H. Yokogoshi e M. Kobayashi, "HYPOTENSIVE EFFECT OF GAMMA-GLUTAMYLMETHYLAMIDE IN SPONTANEOUSLY HYPERTENSIVE RATS", Life sciences, 62(12), 1998, pp. 1065-1068

Abstract

The effect of gamma-glutamylmethylamide(GMA), one of the components of green tea extract, on the blood pressure in spontaneously hypertensive rats (SHR) was investigated. The effect of glutamic acid and r-glutamylethylamide (theanine), which is structually similar to GMA, was also examined. When SHR were injected with glutamic acid (2000mg/kg), the blood pressure was not altered. The same dose of theanine decreased it significantly. GMA administration to SHR reduced the blood pressuresignificantly, and its degree of hypotensive action was more effective than that by theanine administration.

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Documento generato il 05/12/20 alle ore 10:40:32