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Titolo:
HIGH-LEVELS OF ANTICARDIOLIPIN ANTIBODIES IN PATIENTS WITH ABNORMAL EMBRYO MORPHOLOGY WHO ATTENDED AN IN-VITRO FERTILIZATION PROGRAM
Autore:
AZEM F; GEVA E; AMIT A; LERNERGEVA L; SHWARTZ T; BENYOSEF D; YOVEL I; LESSING JB;
Indirizzi:
LIS MATERN HOSP,DEPT OBSTET & GYNECOL,SARA RACINE IVF UNIT,TEL AVIV SOURASKY MED CTR IL-64239 TEL AVIV ISRAEL LIS MATERN HOSP,DEPT OBSTET & GYNECOL,SARA RACINE IVF UNIT,TEL AVIV SOURASKY MED CTR IL-64239 TEL AVIV ISRAEL TEL AVIV UNIV,SACKLER SCH MED IL-69978 TEL AVIV ISRAEL CHAIM SHEBA MED CTR,DEPT CLIN EPIDEMIOL TEL HASHOMER ISRAEL
Titolo Testata:
AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY
fascicolo: 3, volume: 39, anno: 1998,
pagine: 161 - 163
SICI:
1046-7408(1998)39:3<161:HOAAIP>2.0.ZU;2-N
Fonte:
ISI
Lingua:
ENG
Soggetto:
INVITRO FERTILIZATION; FAILURE; RATES;
Keywords:
AUTOIMMUNITY; EMBRYO QUALITY; REPRODUCTION FAILURE;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
19
Recensione:
Indirizzi per estratti:
Citazione:
F. Azem et al., "HIGH-LEVELS OF ANTICARDIOLIPIN ANTIBODIES IN PATIENTS WITH ABNORMAL EMBRYO MORPHOLOGY WHO ATTENDED AN IN-VITRO FERTILIZATION PROGRAM", AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY, 39(3), 1998, pp. 161-163

Abstract

PROBLEM: Recently, it has been suggested that anticardiolipin antibodies (ACAs) may serve as possible markers for reproductive failure. Theassociation between ACAs and embryo morphology in patients undergoingin vitro fertilization (IVF) was investigated. METHOD OF STUDY: This prospective study comprised 117 patients with either tubal factor or unexplained infertility. Embryo morphology was blindly scored from I toIV according to blastomere regularity and the presence of fragments. Anticardiolipin antibodies (immunoglobulin [Ig] G and IgM) were detected. RESULTS: Anticardiolipin antibodies were found in 26 (50%) of the 52 patients with abnormal morphology, compared with 13 (20%) of the 65patients with normal embryo morphology (P = 0.001). No statistically significant differences were found between the prevalence of ACAs among patients with tubal factor and those with unexplained infertility (29.6% and 36.5%, respectively). CONCLUSIONS: Our study shows an association between embryo morphology and the presence of ACAs. This association may explain the low implantation rate and early pregnancy loss in patients with ACAs.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 27/11/20 alle ore 01:22:03