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Titolo:
CONSTRUCTION OF HSC-2DPAGE - A 2-DIMENSIONAL GEL-ELECTROPHORESIS DATABASE OF HEART PROTEINS
Autore:
EVANS G; WHEELER CH; CORBETT JM; DUNN MJ;
Indirizzi:
HAREFIELD HOSP,HEART SCI CTR,IMPERIAL COLL SCH MED,NATL HEART & LUNG INST,DIV CARDIOTHORAC SURG HAREFIELD UB9 6JH MIDDX ENGLAND HAREFIELD HOSP,HEART SCI CTR,IMPERIAL COLL SCH MED,NATL HEART & LUNG INST,DIV CARDIOTHORAC SURG HAREFIELD UB9 6JH MIDDX ENGLAND
Titolo Testata:
Electrophoresis
fascicolo: 3-4, volume: 18, anno: 1997,
pagine: 471 - 479
SICI:
0173-0835(1997)18:3-4<471:COH-A2>2.0.ZU;2-X
Fonte:
ISI
Lingua:
ENG
Soggetto:
UPDATE 1993; MAP; IDENTIFICATION; SWISS-2DPAGE; PLASMA;
Keywords:
ENDOTHELIAL PROTEINS; HEART PROTEINS; MYOCYTE PROTEINS; 2-DIMENSIONAL ELECTROPHORESIS PROTEIN DATABASES; 2-DIMENSIONAL POLYACRYLAMIDE GEL ELECTROPHORESIS; WORLD WIDE WEB;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
25
Recensione:
Indirizzi per estratti:
Citazione:
G. Evans et al., "CONSTRUCTION OF HSC-2DPAGE - A 2-DIMENSIONAL GEL-ELECTROPHORESIS DATABASE OF HEART PROTEINS", Electrophoresis, 18(3-4), 1997, pp. 471-479

Abstract

The dissemination of information relating to the characterisation of proteins from two-dimensional electrophoresis (2-DE) gel databases is essential for their effective utilisation in the study of protein expression in cell biology. Since the inception of the World Wide Web and the pioneering development of SWISS-2DPAGE as a tool for retrieving information on proteins separated by 2-DE, the Internet has become the method of choice for disseminating and accessing information on 2-DE protein databases. At Harefield we have established HSC-2DPAGE which is an advanced interface for accessing protein databases relating to heart disease. The Web site currently includes databases of proteins from human, dog and rat ventricular tissue and a human endothelial cell line. The databases are searchable individually or as a whole by remote keyword searches. Each database is represented by both synthetic (computer generated) and real (scanned gel) clickable images upon which characterised protein spots are highlighted by hyperlinked symbols. The database conforms to all the rules proposed for federated 2-DE protein databases and individual protein entries are linked to other protein databases such as SWISS-PROT by active cross-references. This paper describes the construction of HSC-2DPAGE, its maintenance, and access via the Internet.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 29/11/20 alle ore 05:44:04