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Titolo:
BLOOD COMPATIBLE POLYMERS IN INTENSIVE-CARE UNITS - STATE-OF-THE-ART AND CURRENT ASPECTS OF BIOMATERIALS RESEARCH
Autore:
RAGALLER M; WERNER C; BLEYL J; ADAM S; JACOBASCH HJ; ALBRECHT DM;
Indirizzi:
TECH UNIV DRESDEN,UNIV KLINIKUM CARL GUSTAV CARUS,KLIN ANASTHESIE & INTENS THERAPIE D-01307 DRESDEN GERMANY INST POLYMER RES DRESDEN DRESDEN GERMANY
Titolo Testata:
Kidney international
, , anno: 1998, supplemento:, 64
pagine: 84 - 90
SICI:
0085-2538(1998):<84:BCPIIU>2.0.ZU;2-M
Fonte:
ISI
Lingua:
ENG
Soggetto:
HEPARIN-COATED CIRCUITS; EXTRACORPOREAL MEMBRANE-OXYGENATION; ACUTE-RENAL-FAILURE; CARDIOPULMONARY BYPASS; COMPLEMENT ACTIVATION; PLATELET ACTIVATION; CLINICAL-TRIAL; BIOCOMPATIBILITY; HEMODIALYSIS; CIRCULATION;
Keywords:
ARTIFICIAL ORGANS; BIOCOMPATIBILITY; SYSTEMIC INFLAMMATORY RESPONSE SYNDROME; EXTRACORPOREAL BYPASS; POLYMERS; BIOMATERIALS RESEARCH;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
69
Recensione:
Indirizzi per estratti:
Citazione:
M. Ragaller et al., "BLOOD COMPATIBLE POLYMERS IN INTENSIVE-CARE UNITS - STATE-OF-THE-ART AND CURRENT ASPECTS OF BIOMATERIALS RESEARCH", Kidney international, 1998, pp. 84-90

Abstract

The use of artificial organs in cases of acute renal failure, acute respiratory distress syndrome (ARDS) and multiorgan dysfunction syndrome (MODS) has lead to a significant reduction of mortality. However, the interaction between body and biomaterials results in the activation of the coagulation system and in the induction of systemic inflammatory response syndrome. The necessary anticoagulation may be contraindicated and may even further increase the risk for the patient. This article evaluates the currently applied polymeric materials used in intensive care units (ICU) and gives a possible outlook into future developments. It is emphasized that systematic interdisciplinary research of physicans and biomaterial scientists is essential for the successful development of new polymers with improved biocompatibility. For this purpose a brief overview of analytical techniques for surface characterization is given, and future developments to a fully biocompatible polymer are described.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 03/08/20 alle ore 12:32:31