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Titolo:
FATTY-ACIDS AND BRAIN PEPTIDES
Autore:
YEHUDA S; RABINOVITZ S; CARASSO RL; MOSTOFSKY DI;
Indirizzi:
BAR ILAN UNIV,DEPT PSYCHOL,PSYCHOPHARMACOL LAB IL-52900 RAMAT GAN ISRAEL H YAFFA HOSP,DEPT NEUROL HADERA ISRAEL BOSTON UNIV,DEPT PSYCHOL BOSTON MA 02215
Titolo Testata:
Peptides
fascicolo: 2, volume: 19, anno: 1998,
pagine: 407 - 419
SICI:
0196-9781(1998)19:2<407:FABP>2.0.ZU;2-I
Fonte:
ISI
Lingua:
ENG
Soggetto:
VASOACTIVE-INTESTINAL-PEPTIDE; CORTICOTROPIN-RELEASING FACTOR; ANTERIOR-PITUITARY-CELLS; GROWTH-HORMONE RELEASE; MESSENGER-RNA EXPRESSION; OPIOID RECEPTOR-BINDING; CENTRAL-NERVOUS-SYSTEM; ALPHA-LINOLENIC ACID; ARACHIDONIC-ACID; RAT-BRAIN;
Keywords:
FATTY ACIDS; LINOLEIC; ALPHA-LINOLENIC; N-3; N-6; RATIO; NEURONAL MEMBRANE; RELEASING FACTORS; LEARNING; PAIN; THERMOREGULATION;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
167
Recensione:
Indirizzi per estratti:
Citazione:
S. Yehuda et al., "FATTY-ACIDS AND BRAIN PEPTIDES", Peptides, 19(2), 1998, pp. 407-419

Abstract

The role of fatty acids (FA) as a mediator and modulator of central nervous system activity in general, and peptides in particular, is onlyrecently becoming understood. This paper reviews numerous findings concerned with the activity of fatty acids, particularly with their interaction with diverse neurochemical systems and their consequences for better understanding neurotransmitters, hormones and peptides. The effects include FA as precursors in the manufacture of neurochemical elements, including enzymes, neurotransmitters, and hormones. Of particular interest is the important changes in neuronal membrane composition that have been attributed to FA. Such changes may account for the changes in thermoregulation, learning, and other functions that accompany dietary manipulation of FA intake. While the total level of FA has beenthe object of many investigations, this report addresses the need to focus on the ratio of FA, especially alpha-linolenic/linoleic acid, which has been shown to be a critical factor in a number of research studies. (C) 1998 Elsevier Science Inc.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 21/09/20 alle ore 16:10:23