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Titolo:
EFFICACY OF CORONARY STENTING VERSUS BALLOON ANGIOPLASTY IN SMALL COROLLARY ARTERIES
Autore:
SAVAGE MP; FISCHMAN DL; RAKE R; LEON MB; SCHATZ RA; PENN I; NOBUYOSHI M; MOSES J; HIRSHFELD J; HEUSER R; BAIM D; CLEMAN M; BRINKER J; GEBHARDT S; GOLDBERG S;
Indirizzi:
THOMAS JEFFERSON UNIV,JEFFERSON MED COLL,DIV CARDIOL,SUITE 410,COLL BLDG,1025 WALNUT ST PHILADELPHIA PA 19107 WASHINGTON HOSP CTR WASHINGTON DC 20010 SCRIPPS RES INST LA JOLLA CA 00000 VICTORIA GEN HOSP HALIFAX NS B3H 2Y9 CANADA KOKURA MEM HOSP KYUSHU JAPAN LENOX HILL HOSP NEW YORK NY 10021 HOSP UNIV PENN PHILADELPHIA PA 19104 ARIZONA HEART INST PHOENIX AZ 00000 BETH ISRAEL HOSP BOSTON MA 02215 YALE UNIV NEW HAVEN CT 00000 JOHNS HOPKINS UNIV HOSP BALTIMORE MD 21287 MASSACHUSETTS GEN HOSP BOSTON MA 02114
Titolo Testata:
Journal of the American College of Cardiology
fascicolo: 2, volume: 31, anno: 1998,
pagine: 307 - 311
SICI:
0735-1097(1998)31:2<307:EOCSVB>2.0.ZU;2-U
Fonte:
ISI
Lingua:
ENG
Soggetto:
MULTICENTER-REGISTRY; EXPANDABLE-STENT; IMPLANTATION; RESTENOSIS; PLACEMENT; DISEASE;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
12
Recensione:
Indirizzi per estratti:
Citazione:
M.P. Savage et al., "EFFICACY OF CORONARY STENTING VERSUS BALLOON ANGIOPLASTY IN SMALL COROLLARY ARTERIES", Journal of the American College of Cardiology, 31(2), 1998, pp. 307-311

Abstract

Objectives. The goal of this study was to compare the efficacy of elective stent implantation and balloon angioplasty for new lesions in small coronary arteries. Background. Palmaz-Schatz stents have been designed and approved by the Food and Drug Administration for use in coronary arteries with diameters greater than or equal to 3.0 mm. The efficacy of elective stent placement in smaller vessels has not been determined. Methods. By quantitative coronary angiography, 331 patients in the Stent Restenosis Study (STRESS) I-II were determined to have a reference vessel <3.0 mm in diameter, Of these, 163 patients were randomlyassigned to stenting (mean diameter 2.69 +/- 0.21 mm), and 168 patients were assigned to angioplasty (mean diameter 2.64 +/- 0.24 mm). The primary end point was restenosis, defined as greater than or equal to 50% diameter stenosis at 6-month follow up angiography. Clinical eventrates at 1 year were assessed, Results. Baseline clinical and angiographic characteristics were similar in the two groups, Procedural success was achieved in 100% of patients assigned to stenting and in 92% ofpatients assigned to angioplasty (p < 0.001). Abrupt closure within 30 days occurred in 3.6% of patients in both groups. Compared with angioplasty, stenting conferred a significantly larger postprocedural lumen diameter (2.26 vs. 1.80 mm, p < 0.001) and a larger lumen at 6 months (1.54 vs, 1.27 mm, p < 0.001). Restenosis (greater than or equal to 50% diameter stenosis at follow-up) occurred in 34% of patients assigned to stenting and in 55% of patients assigned to angioplasty (p < 0.001). At 1 year, event-free survival was achieved in 78% of the stent group and in 67% of the angioplasty group (p = 0.019). Conclusions. These findings suggest that elective stent placement provides superior angiographic and clinical outcomes than balloon angioplasty in vessels slightly smaller than 3 mm. (C) 1998 by the American College of Cardiology.

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Documento generato il 26/09/20 alle ore 01:04:29