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Titolo:
NEUREGULINS IN GLIAL-CELLS
Autore:
RAABE TD; FRANCIS A; DEVRIES GH;
Indirizzi:
EDWARD HINES JR VET ADM HOSP,RES SERV 151 HINES IL 60141 EDWARD HINES JR VET ADM HOSP,RES SERV 151 HINES IL 60141 LOYOLA UNIV,MED CTR,DEPT CELL BIOL NEUROBIOL & ANAT MAYWOOD IL 60153 LOYOLA UNIV,MED CTR,NEUROSCI PROGRAM MAYWOOD IL 60153
Titolo Testata:
Neurochemical research
fascicolo: 3, volume: 23, anno: 1998,
pagine: 311 - 318
SICI:
0364-3190(1998)23:3<311:>2.0.ZU;2-W
Fonte:
ISI
Lingua:
ENG
Soggetto:
NEU DIFFERENTIATION FACTOR; RECEPTOR-INDUCING PROTEIN; EPIDERMAL GROWTH-FACTOR; SCHWANN-CELLS; SIGNAL-TRANSDUCTION; CARDIAC DEVELOPMENT; PERIPHERAL-NERVE; PROLIFERATION; EXPRESSION; SURVIVAL;
Keywords:
GROWTH FACTOR; AUTOCRINE; NEUREGULIN; OLIGODENDROCYTE; SCHWANN CELL; ASTROCYTE;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
54
Recensione:
Indirizzi per estratti:
Citazione:
T.D. Raabe et al., "NEUREGULINS IN GLIAL-CELLS", Neurochemical research, 23(3), 1998, pp. 311-318

Abstract

The role of growth factors in controlling the development of glial cells in both the peripheral and central nervous systems has been investigated for a number of years. The recent discovery of a new family of growth factors termed the neuregulins (NRGs) has led to an explosion of information concerning the putative role of these growth factors in the development of Schwann cells (SC), oligodendrocytes (OLG), and astrocytes. Many of these previous studies have focused on the effects ofexogenous NRGs on glial cell development and differentiation. We now review the evidence that these glial cells themselves produce NRGs anddiscuss the major implications of these findings with respect to glial cell development and diseases which affect glial cell function. We also discuss the potential role of endogenous NRGs following neural injury.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 13/07/20 alle ore 20:29:33