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Titolo:
AN INVESTIGATION OF GLUCOSE EFFECTS ON LEARNING AND MEMORY IMPAIRMENTS INDUCED BY HIGH-FAT DIETS AND ENVIRONMENTAL-FACTORS
Autore:
GREENWOOD CE; WINOCUR G;
Indirizzi:
BAYCREST CTR GERIATR CARE,KUNIN LUNENFELD CLIN RES UNIT N YORK ON CANADA BAYCREST CTR GERIATR CARE,ROTMAN RES INST N YORK ON CANADA
Titolo Testata:
Brain and cognition
fascicolo: 3, volume: 35, anno: 1997,
pagine: 415 - 418
SICI:
0278-2626(1997)35:3<415:AIOGEO>2.0.ZU;2-S
Fonte:
ISI
Lingua:
ENG
Tipo documento:
Article
Natura:
Periodico
Citazioni:
NO
Recensione:
Indirizzi per estratti:
Citazione:
C.E. Greenwood e G. Winocur, "AN INVESTIGATION OF GLUCOSE EFFECTS ON LEARNING AND MEMORY IMPAIRMENTS INDUCED BY HIGH-FAT DIETS AND ENVIRONMENTAL-FACTORS", Brain and cognition, 35(3), 1997, pp. 415-418

Abstract

We previously demonstrated that feeding rats high fat diets impairs performance on learning and memory tests. This study examined the combined effects of environmental factors and diet on cognition to determine if glucose administration could enhance performance adversely affected by these factors. Subjects were tested on a variable interval delayed alternation task which measures learning and memory functions that differentially involve specific brain regions. The results confirmed the negative effects of high fat diets and showed that environmental enrichment improved acquisition of the basic habit. By comparison, glucose selectively enhanced trial-specific memory performance at longer delays. We conclude that high fat diets generally disrupt cognitive function. The enriched environment reduced learning impairment associated with frontal lobe function whereas glucose mediated its beneficial effects on hippocampus-related memory function.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 09/07/20 alle ore 00:34:52