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Titolo:
THE ANDROGEN-RECEPTOR-GENE-MUTATIONS-DATABASE
Autore:
GOTTLIEB B; LEHVASLAIHO H; BEITEL LK; LUMBROSO R; PINSKY L; TRIFIRO M;
Indirizzi:
SIR MORTIMER B DAVIS JEWISH HOSP,LADY DAVIS INST MED RES,3755 COTE STE CATHERINE RD QUEBEC CITY PQ H3T 2E1 CANADA SIR MORTIMER B DAVIS JEWISH HOSP,LADY DAVIS INST MED RES QUEBEC CITY PQ H3T 1E2 CANADA MCGILL UNIV,DEPT MED QUEBEC CITY PQ H3T 1E2 CANADA MCGILL UNIV,DEPT BIOL QUEBEC CITY PQ H3T 1E2 CANADA MCGILL UNIV,DEPT HUMAN GENET QUEBEC CITY PQ H3T 1E2 CANADA JOHN ABBOTT COLL,DEPT BIOL QUEBEC CITY PQ H9X 3L9 CANADA EUROPEAN BIOINFORMAT INST,EMBL OUTSTN CAMBRIDGE CB10 1SD ENGLAND
Titolo Testata:
Nucleic acids research
fascicolo: 1, volume: 26, anno: 1998,
pagine: 234 - 238
SICI:
0305-1048(1998)26:1<234:TA>2.0.ZU;2-I
Fonte:
ISI
Lingua:
ENG
Soggetto:
REIFENSTEIN SYNDROME; PROSTATE-CANCER; BINDING DOMAIN; RESISTANCE; CELLS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
28
Recensione:
Indirizzi per estratti:
Citazione:
B. Gottlieb et al., "THE ANDROGEN-RECEPTOR-GENE-MUTATIONS-DATABASE", Nucleic acids research, 26(1), 1998, pp. 234-238

Abstract

The current version of the androgen receptor (AR) gene mutations database is described, The total number of reported mutations has risen from 272 to 309 in the past year, We have expanded the database: (i) by giving each entry an accession number; (ii) by adding information on the length of polymorphic polyglutamine (polyGln) and polyglycine (polyGly) tracts in exon 1; (iii) by adding information on large gene deletions; (iv) by providing a direct link with a completely searchable database (courtesy EMBL-European Bioinformatics Institute), The addition of the exon 1 polymorphisms is discussed in light of their possible relevance as markers for predisposition to prostate or brest cancer. Thedatabase is also available on the internet (http://www.mcgill.ca/androgendb/), from EMBL-European Bioinformatics Institute (ftp.ebi.ac.uk/pub/databases/androgen), or as a Macintosh FilemakerPro or Word file (MC33@musica.mcgill.ca).

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 24/09/20 alle ore 21:15:55