Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
ACOUSTIC TRAUMA CAUSES REVERSIBLE STIFFNESS CHANGES IN AUDITORY SENSORY CELLS
Autore:
CHAN E; SUNESON A; ULFENDAHL M;
Indirizzi:
KAROLINSKA INST,DEPT PHYSIOL & PHARMACOL S-17177 STOCKHOLM SWEDEN KAROLINSKA INST,DEPT PHYSIOL & PHARMACOL S-17177 STOCKHOLM SWEDEN DEF RES ESTAB,DIV HUMAN SCI S-17290 STOCKHOLM SWEDEN KAROLINSKA HOSP,KING GUSTAF V RES INST,ENT RES LAB S-17176 STOCKHOLM SWEDEN
Titolo Testata:
Neuroscience
fascicolo: 3, volume: 83, anno: 1998,
pagine: 961 - 968
SICI:
0306-4522(1998)83:3<961:ATCRSC>2.0.ZU;2-A
Fonte:
ISI
Lingua:
ENG
Soggetto:
OUTER HAIR-CELLS; TEMPORARY THRESHOLD SHIFT; ACTIVE FORCE GENERATION; IMPULSE-NOISE; NERVE-FIBERS; HEARING-LOSS; EXPOSURE; COCHLEA; ORGAN; CORTI;
Keywords:
ACOUSTIC TRAUMA; HEARING; IMPULSE NOISE; MECHANICS; OUTER HAIR CELLS; STIFFNESS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
43
Recensione:
Indirizzi per estratti:
Citazione:
E. Chan et al., "ACOUSTIC TRAUMA CAUSES REVERSIBLE STIFFNESS CHANGES IN AUDITORY SENSORY CELLS", Neuroscience, 83(3), 1998, pp. 961-968

Abstract

A common cause of hearing impairment is exposure to loud noise. Recent research has demonstrated that the auditory mechanosensory cells areessential for normal hearing sensitivity and frequency selectivity. However, little is known about the effect of noise exposure on the mechanical properties of the auditory sensory cells. Here we report a significant reduction in the stiffness and cell length of the outer hair cells after impulse noise exposure, suggesting that mechanical changes at the cellular level are involved in noise-induced hearing loss. There is a recovery of the cellular stiffness and cell length over a two-week period, indicating an activation of cellular repair mechanisms forrestoring the auditory function following noise trauma. The reduced stiffness observed at the cellular level is likely to be the cause for the downward shift of the characteristic frequency seen following acoustic trauma. The deterioration and the recovery of the mechanical properties of outer hair cells may form important underlying factors in all kinds of noise-induced hearing loss. (C) 1998 IBRO. Published by Elsevier Science Ltd.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 01/12/20 alle ore 07:29:11