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Titolo:
MAGNETIC-RESONANCE-IMAGING FINDINGS IN 22 CASES OF MYELITIS - COMPARISON BETWEEN PATIENTS WITH AND WITHOUT MULTIPLE-SCLEROSIS
Autore:
BAKSHI R; KINKEL PR; MECHTLER LL; BATES VE; LINDSAY BD; ESPOSITO SE; KINKEL WR;
Indirizzi:
LUCY DENT IMAGING CTR,3 GATES CIRCLE BUFFALO NY 14209 SUNY BUFFALO,SCH MED & BIOMED SCI,DENT NEUROL INST BUFFALO NY 14260 SUNY BUFFALO,SCH MED & BIOMED SCI,MILLARD FILLMORE HLTH SYST BUFFALO NY 14260 SUNY BUFFALO,SCH MED & BIOMED SCI,DEPT NEUROL BUFFALO NY 14260
Titolo Testata:
European journal of neurology
fascicolo: 1, volume: 5, anno: 1998,
pagine: 35 - 48
SICI:
1351-5101(1998)5:1<35:MFI2CO>2.0.ZU;2-H
Fonte:
ISI
Lingua:
ENG
Soggetto:
ACUTE TRANSVERSE MYELOPATHY; ACUTE DISSEMINATED ENCEPHALOMYELITIS; SPINAL-CORD; FOLLOW-UP; MRI FINDINGS; BRAIN-STEM; APPEARANCE;
Keywords:
TRANSVERSE MYELITIS; SPINAL CORD; MULTIPLE SCLEROSIS; MAGNETIC RESONANCE IMAGING; MYELOPATHY;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
40
Recensione:
Indirizzi per estratti:
Citazione:
R. Bakshi et al., "MAGNETIC-RESONANCE-IMAGING FINDINGS IN 22 CASES OF MYELITIS - COMPARISON BETWEEN PATIENTS WITH AND WITHOUT MULTIPLE-SCLEROSIS", European journal of neurology, 5(1), 1998, pp. 35-48

Abstract

We reviewed the magnetic resonance imaging (MRI) database of the DentNeurologic Institute to study the abnormal findings in myelitis. We identified 22 patients, and compared non-MS-related acute transverse myelitis (ATM, n = 9), to myelitis associated with multiple sclerosis (MS-myelitis, n = 13). The ATM patients were significantly older than MSpatients at the time of the myelitis diagnosis (mean age 46 vs 35, p < 0.05). ATM appeared as a ''longitudinal myelitis'', with fusiform cord expansion on T-1-weighted images and intramedullary increased signal on T-2-weighted images, each involving multiple spinal levels (mean = 7-8). However, MS-myelitis lesions appeared focal, involving significantly fewer spinal levels (mean = 1-2, p < 0.001), although the lesions were equally likely to expand the cord. Four (42%) of the ATM lesions showed abnormal, variable enhancement, whereas none of the MS myelitis lesions enhanced. Cranial MRI was more likely to be normal in ATM (78%) than in MS-myelitis patients (15%, p < 0.001). Although readily distinguishable from lesions due to MS, the various etiologies for ATM, including post-infectious (n = 2), post-vaccination (n = 3), and idiopathic (n = 4) were indistinguishable on MRI. The MRI findings of an extensively lesioned, swollen cord, suspicious for an intramedullary tumor and providing a temptation for a biopsy, may reflect a non-neoplastic inflammatory disorder.

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Documento generato il 03/07/20 alle ore 16:51:18