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Titolo:
EXERCISE-INDUCED SILENT-MYOCARDIAL-ISCHEMIA IN MASTER ATHLETES
Autore:
KATZEL LI; FLEG JL; BUSBYWHITEHEAD MJ; SORKIN JD; BECKER LC; LAKATTA EG; GOLDBERG AP;
Indirizzi:
BALTIMORE VA MED CTR,GRECC 18,10 N GREENE ST BALTIMORE MD 21201 UNIV MARYLAND,SCH MED,DEPT MED,DIV GERONTOL BALTIMORE MD 21201 JOHNS HOPKINS UNIV,SCH MED,DEPT MED,DIV CARDIOL BALTIMORE MD 21205 JOHNS HOPKINS UNIV,SCH MED,DEPT MED,DIV GERIATR MED & GERONTOL BALTIMORE MD 21205 JOHNS HOPKINS BAYVIEW MED CTR BALTIMORE MD 00000 NIA,GERONTOL RES CTR,CARDIOVASC SCI LAB,NIH BALTIMORE MD 21224 NIA,GERONTOL RES CTR,CLIN INVEST LAB,METAB SECT,NIH BALTIMORE MD 21224
Titolo Testata:
The American journal of cardiology
fascicolo: 3, volume: 81, anno: 1998,
pagine: 261 - 265
SICI:
0002-9149(1998)81:3<261:ESIMA>2.0.ZU;2-H
Fonte:
ISI
Lingua:
ENG
Soggetto:
CORONARY-ARTERY DISEASE; DENSITY-LIPOPROTEIN CHOLESTEROL; APOLIPOPROTEIN-E ALLELES; E POLYMORPHISM; OLDER MEN; RISK; PERFORMANCE; VOLUNTEERS; PREVALENCE; PHENOTYPE;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
20
Recensione:
Indirizzi per estratti:
Citazione:
L.I. Katzel et al., "EXERCISE-INDUCED SILENT-MYOCARDIAL-ISCHEMIA IN MASTER ATHLETES", The American journal of cardiology, 81(3), 1998, pp. 261-265

Abstract

High-physical activity levels are associated with reduced risk of symptomatic coronary artery disease (CAD). However, there are a number ofreports of exercise-related sudden death and myocardial infarction inaerobically trained athletes, This study compared the prevalence of exercise-induced silent myocardial ischemia on maximum graded exercise tests with tomographic thallium scintigraphy in 70 master male athletes (63 +/- 6 years, mean +/- SD) (maximum aerobic capacity, (V) over dot O(2)max >40 ml/kg/min) and in 85 healthy untrained men (61 +/- 7 years) with no history of CAD, The prevalence of silent ischemia (exercise-induced ST-segment depression on electrocardiogram and perfusion abnormalities on thallium scintigraphy) was similar in athletes and untrained men; 16% of the athletes (11 of 70) had silent ischemia compared with 21% of the untrained men (chi-square = 0.81, p = 0.36), No athletes had hyperlipidemia, systemic hypertension, or diabetes mellitus, However, the apolipoprotein E4 allele was present in 9 of the 11 athletes with silent ischemia compared with 2 of 32 athletes with normal exercise tests (chi-square = 24, p = 0.0001), These results suggest that older male athletes with the apolipoprotein E4 allele are at increased risk for the development of exercise-induced silent ischemia. (C) 1998by Excerpta Medica, Inc.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 27/11/20 alle ore 00:31:12