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Titolo:
SQUAMOUS INTRAEPITHELIAL LESIONS IN CERVICAL SMEARS OF HUMAN IMMUNODEFICIENCY VIRUS-SEROPOSITIVE ADOLESCENTS
Autore:
CALORE EE; CAVALIERE MJ; CALORE NMP;
Indirizzi:
INST INFECTOL EMILIO RIBAS,SECAO ANAT PATOL,AV DR ARNALDO,165 BR-01246001 SAO PAULO BRAZIL
Titolo Testata:
Diagnostic cytopathology
fascicolo: 2, volume: 18, anno: 1998,
pagine: 91 - 92
SICI:
8755-1039(1998)18:2<91:SILICS>2.0.ZU;2-T
Fonte:
ISI
Lingua:
ENG
Soggetto:
HUMAN PAPILLOMAVIRUS INFECTION; PAPANICOLAOU SMEARS; WOMEN; ABNORMALITIES; NEOPLASIA; RISK;
Keywords:
HPV INFECTION; CERVIX; EPITHELIUM; HIV; AIDS; ADOLESCENCE;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
12
Recensione:
Indirizzi per estratti:
Citazione:
E.E. Calore et al., "SQUAMOUS INTRAEPITHELIAL LESIONS IN CERVICAL SMEARS OF HUMAN IMMUNODEFICIENCY VIRUS-SEROPOSITIVE ADOLESCENTS", Diagnostic cytopathology, 18(2), 1998, pp. 91-92

Abstract

Various authors have reported a high rate of human papillomavirus (HPV) infection and HPV-related neoplasias in human immunodeficiency virus (HN)-seropositive women. On the other hand young women are most susceptible to cervical infection because of immaturity of the the cervix,as it appears that HPV has more access to the basal cells of the differentiating epithelium. The purpose of the present work was to study cervical smears of 82 adolescent HIV-seropositive women (13-21 years ofage) to search Sor cytological evidence of cervical intraepithelial neoplasias. Twenty-one cases showed characteristic features of HPV infection and squamous intraepithelial lesions (Sa; 25.6%). Sixteen cases aged from 17 to 21 years (mean age 19.5 years) had low-grade SIL (LSIL; 19.5%) and five cases aged from 18 to 21 years (mean age 20.2 years)had high-grade SIL (HSIL; 6.1%). There was no significant difference between the mean age of patients with LSIL and HSIL. Two cases had atypical squamous cells of undetermined significance (ASCUS), In the present work it was found that HIV-seropositive adolescents have a high risk Soi preneoplastic lesions of the cervix (25.6%) as well as a high incidence of more aggressive lesions (6.1% of HSIL) when compared to the general population of adolescents. adolescents. As it can be assumedthat, if the age of acquisition of the the infection in both groups (in the general population and HN-seropositive women) is the same, it is probable that HIV infection in adolescents not only increases the frequency of HPV infections but also facilities the evolution to more aggressive preneoplastic lesions of the cervix due to HPV Diagn. (C) 1998 Wiley-Liss, Inc.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 25/02/20 alle ore 11:45:36