Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
COEXPRESSION OF NEUROPEPTIDE-Y AND VASOACTIVE INTESTINAL POLYPEPTIDE IN PELVIC PLEXUS NEURONS INNERVATING THE UTERUS AND CERVIX IN THE RAT
Autore:
HOUDEAU E; BOYER PA; ROUSSEAU A; ROUSSEAU JP;
Indirizzi:
UNIV PARIS 06,INRA,CNRS URA 1449,LAB PHYSIOL REPROD,GRP NEUROPHYSIOL,7 QUAI ST BERNARD F-75252 PARIS 05 FRANCE UNIV PARIS 06,LAB CYTOL,CNRS URA 1488 F-75252 PARIS 05 FRANCE
Titolo Testata:
Cell and tissue research
fascicolo: 2, volume: 288, anno: 1997,
pagine: 285 - 292
SICI:
0302-766X(1997)288:2<285:CONAVI>2.0.ZU;2-4
Fonte:
ISI
Lingua:
ENG
Soggetto:
PIG UTERINE ARTERY; NON-NORADRENERGIC AXONS; MYOMETRIAL BLOOD-FLOW; FEMALE GENITAL-TRACT; GUINEA-PIG; PARACERVICAL GANGLION; GENITOURINARY TRACT; REPRODUCTIVE-TRACT; VIP; NERVES;
Keywords:
NPY; VIP; PELVIC GANGLIA; IMMUNOCYTOCHEMISTRY; IN SITU HYBRIDIZATION; RETROGRADE TRACING (FLUOROGOLD); GENITAL TRACT; RAT (SPRAGUE DAWLEY);
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
37
Recensione:
Indirizzi per estratti:
Citazione:
E. Houdeau et al., "COEXPRESSION OF NEUROPEPTIDE-Y AND VASOACTIVE INTESTINAL POLYPEPTIDE IN PELVIC PLEXUS NEURONS INNERVATING THE UTERUS AND CERVIX IN THE RAT", Cell and tissue research, 288(2), 1997, pp. 285-292

Abstract

The present study investigates the distribution and coexpression of neuropeptide Y (NPY) and vasoactive intestinal peptide (VIP) in neurones of the accessory ganglion (AG), hypogastric plexus (HP) and paracervical ganglion (PCG), which compose the pelvic plexus in the female rat. Nerve cell bodies immunoreactive for NPY and VIP represent 84% and 46% of the neurone population in the PCG, respectively, while immunoreactivity for each peptide is observed in about 90% of the AG and HP neurones. Adjacent sections immunostained for NPY and VIP, as well as theuse of immunocytochemistry combined with in situ hybridization show that 92% of the VIP-containing neurones in the pelvic plexus also contain NPY. In addition, a retrograde tracing study performed in combination with immunocytochemistry demonstrates that pelvic plexus neurones project preferentially to the lower part of the uterus and to the cervix, and that about 95% of these projecting neurones contain VIP. Taken together, our findings indicate that in the female rat, neurones of the pelvic plexus projecting to the lower genital tract mainly coexpressVIP and NPY, and supply nerve fibres to the vascular and nonvascular smooth muscle in the uterocervical region. Since NPY and VIP exert distinct effects according to the target tissue, our results suggest thatneurones coexpressing these peptides play important roles in the local regulation of the vascular bed and motor activity of the lower genital tract.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 24/11/20 alle ore 14:21:41