Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
GENE-THERAPY FOR INFECTIOUS-DISEASES
Autore:
BUNNELL BA; MORGAN RA;
Indirizzi:
NATL HUMAN GENOME RES INST,CLIN GENE THERAPY BRANCH,NIH,BLDG 10,ROOM 10C103,9000 ROCKVILLE PIKE BETHESDA MD 20892 NATL HUMAN GENOME RES INST,CLIN GENE THERAPY BRANCH,NIH BETHESDA MD 20892
Titolo Testata:
Clinical microbiology reviews
fascicolo: 1, volume: 11, anno: 1998,
pagine: 42 -
SICI:
0893-8512(1998)11:1<42:GFI>2.0.ZU;2-G
Fonte:
ISI
Lingua:
ENG
Soggetto:
HUMAN-IMMUNODEFICIENCY-VIRUS; HERPES-SIMPLEX VIRUS; HUMAN T-CELLS; HUMAN PAPILLOMAVIRUS TYPE-18; RECOMBINANT SOLUBLE CD4; ALLOGENEIC BONE-MARROW; INHIBITS HIV-1 REPLICATION; SINGLE-CHAIN ANTIBODY; REV ACTIVATION DOMAIN; EXPRESS ANTISENSE RNA;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
166
Recensione:
Indirizzi per estratti:
Citazione:
B.A. Bunnell e R.A. Morgan, "GENE-THERAPY FOR INFECTIOUS-DISEASES", Clinical microbiology reviews, 11(1), 1998, pp. 42

Abstract

Gene therapy is being investigated as an alternative treatment for a wide range of infectious diseases that are not amenable to standard clinical management. Approaches to gene therapy for infectious diseases can be divided into thr ee broad categories: (i) gene therapies based on nucleic acid moieties, including antisense DNA or RNA, RNA decoys, and catalytic RNA moieties (ribozymes); (ii) protein approaches such as transdominant negative proteins and single-chain antibodies; and (iii) immunotherapeutic approaches involving generic vaccines or. pathogen-specific lymphocytes. It is further possible that combinations of the afore mentioned approaches will be used simultaneously to inhibit multiple stages of the life cycle of the infectious agent.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 28/09/20 alle ore 11:06:41