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Titolo:
VENEZUELAN EQUINE ENCEPHALITIS FEBRILE CASES AMONG HUMANS IN THE PERUVIAN AMAZON RIVER REGION
Autore:
WATTS DM; CALLAHAN J; ROSSI C; OBERSTE MS; ROEHRIG JT; WOOSTER MT; SMITH JF; CROPP CB; GENTRAU EM; KARABATSOS N; GUBLER D; HAYES CG;
Indirizzi:
USN,MED RES INST DETACHMENT,NAMRID,UNIT 3800 APO AA 34031 USA,MED RES INST INFECT DIS,FT DETRICK FREDERICK MD 21702 CTR DIS CONTROL & PREVENT,ARBOVIRUS RES BRANCH,DIV VECTOR BORNE INFECT DIS FT COLLINS CO 80522 PERUVIAN MINIST HLTH IQUITOS PERU USN,DEPT INFECT DIS,MED RES INST BETHESDA MD 20889
Titolo Testata:
The American journal of tropical medicine and hygiene
fascicolo: 1, volume: 58, anno: 1998,
pagine: 35 - 40
SICI:
0002-9637(1998)58:1<35:VEEFCA>2.0.ZU;2-2
Fonte:
ISI
Lingua:
ENG
Soggetto:
MONOCLONAL-ANTIBODIES; HEMORRHAGIC-FEVER; SOUTH-AMERICA; VIRUS; IDENTIFICATION; EPITOPES; TC-83;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
34
Recensione:
Indirizzi per estratti:
Citazione:
D.M. Watts et al., "VENEZUELAN EQUINE ENCEPHALITIS FEBRILE CASES AMONG HUMANS IN THE PERUVIAN AMAZON RIVER REGION", The American journal of tropical medicine and hygiene, 58(1), 1998, pp. 35-40

Abstract

A survey was conducted from October 1, 1993 to June 30, 1995 to determine the arboviral etiologies of febrile illnesses in the city of Iquitos in the Amazon River Basin of Peru. The study subjects were patients who were enrolled at medical care clinics or in their homes by Peruvian Ministry of Health (MOH) workers as part of the passive and activedisease surveillance program of the MOH. The clinical criterion for enrollment was the diagnosis of a suspected viral-associated, acute, undifferentiated febrile illness of less than or equal to 5 days duration. A total of 598 patients were enrolled in the study. Demographic information, medical history, clinical data, and blood samples were obtained from each patient. The more common clinical features were fever, headache, myalgia, arthralgia, retro-ocular pain, and chills. Sera weretested for virus by the newborn mouse and cell culture assays. Viral isolates were identified initially by immunofluorescence using polyclonal antibody. An ELISA using viral-specific monoclonal antibodies and nucleotide sequence analysis were used to determine the specific variety of the viruses. In addition, thin and thick blood smears were observed for malaria parasites. Venezuelan equine encephalitis (VEE) virus subtype I, variety ID virus was isolated from 10 cases, including three cases in October, November, and December 1993, five cases in Januaryand February 1994, and two cases in June 1995. The ELISA for IgM and IgG antibody indicated that VEE virus was the cause of an additional four confirmed and four presumptive cases, including five from January through March 1994 and three in August 1994. Sixteen cases were positive for malaria. The 18 cases of VEE occurred among military recruits (n = 7), agriculture workers (n = 3), students (n = 3), and general laborers (n = 5). These data indicated that an enzootic strain of VEE virus was the cause of at least 3% (18 of 598) of the cases of febrile illnesses studied in the city of Iquitos in the Amazon Basin region of Peru.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 23/09/20 alle ore 22:08:54