Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
NOISE-INDUCED TRANSIENT MICROLESIONS IN THE CELL-MEMBRANES OF AUDITORY HAIR-CELLS
Autore:
MULROY MJ; HENRY WR; MCNEIL PL;
Indirizzi:
MED COLL GEORGIA,DEPT ANAT & CELLULAR BIOL AUGUSTA GA 30912
Titolo Testata:
Hearing research
fascicolo: 1-2, volume: 115, anno: 1998,
pagine: 93 - 100
SICI:
0378-5955(1998)115:1-2<93:NTMITC>2.0.ZU;2-F
Fonte:
ISI
Lingua:
ENG
Soggetto:
TEMPORARY THRESHOLD SHIFT; ALLIGATOR LIZARD; FLUORESCENT DYES; COCHLEA; MODEL; EAR;
Keywords:
NOISE-INDUCED HEARING LOSS; TEMPORARY THRESHOLD SHIFT; CELL MEMBRANE WOUNDING; HAIR CELL MEMBRANE LESION; LIZARD;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
19
Recensione:
Indirizzi per estratti:
Citazione:
M.J. Mulroy et al., "NOISE-INDUCED TRANSIENT MICROLESIONS IN THE CELL-MEMBRANES OF AUDITORY HAIR-CELLS", Hearing research, 115(1-2), 1998, pp. 93-100

Abstract

Several types of nonauditory cells recover from transitory mechanically induced microlesions in their cell membranes. We report evidence that hair cells in the auditory papilla of the alligator lizard sufferedsimilar membrane wounding when exposed to noise loud enough to inducea temporary threshold shift. Lucifer yellow, a molecular marker that does not normally penetrate through the cell membrane into the cytoplasm, was introduced into the extracellular fluid bathing the basolateral membrane of the hair cells. We assessed the effect of loud noise on the function of the ear by measuring compound action potentials of theauditory nerve before exposure to the noise, immediately after cessation of the noise, and after recovering overnight. Hair cells that wereexposed to the noise took up much more Lucifer yellow than hair cellsthat were not exposed. We propose that the Lucifer yellow entered thehair cells via noise-induced lesions in their cell membranes, and that the cells were able to survive and recover functionally. (C) 1998 Elsevier Science B.V.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 29/11/20 alle ore 00:28:35