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Titolo:
ANTIBODIES TO THE AXOLEMMA-ENRICHED FRACTION IN THE CEREBROSPINAL-FLUID AND SERUM OF PATIENTS WITH MULTIPLE-SCLEROSIS AND OTHER NEUROLOGICAL DISEASES
Autore:
RAWES JA; CALABRESE VP; KHAN OA; DEVRIES GH;
Indirizzi:
EDWARD HINES JR VET ADM HOSP,RES SERV 151,5TH & ROOSEVELT RD HINES IL60141 EDWARD HINES JR VET ADM HOSP,RES SERV 151 HINES IL 60141 UNIV MARYLAND,DEPT NEUROL BALTIMORE MD 21201 VIRGINIA COMMONWEALTH UNIV,MED COLL VIRGINIA,DEPT NEUROL RICHMOND VA 23298 VIRGINIA COMMONWEALTH UNIV,MED COLL VIRGINIA,DEPT BIOCHEM & MOL BIOPHYS RICHMOND VA 23298
Titolo Testata:
Multiple sclerosis
fascicolo: 6, volume: 3, anno: 1997,
pagine: 363 - 369
SICI:
1352-4585(1997)3:6<363:ATTAFI>2.0.ZU;2-V
Fonte:
ISI
Lingua:
ENG
Soggetto:
SCHWANN-CELLS; IGG; OLIGODENDROCYTES; AUTOANTIBODIES; PATHOLOGY; PROTEIN; NERVE; AXONS; BANDS; CNS;
Keywords:
MULTIPLE SCLEROSIS; AXOLEMMA-ENRICHED FRACTION; ENZYME-LINKED IMMUNOSORBENT ESSAY; IMMUNOGLOBULIN G; AUTOANTIBODY; AUTOANTIGEN;
Tipo documento:
Article
Natura:
Periodico
Citazioni:
40
Recensione:
Indirizzi per estratti:
Citazione:
J.A. Rawes et al., "ANTIBODIES TO THE AXOLEMMA-ENRICHED FRACTION IN THE CEREBROSPINAL-FLUID AND SERUM OF PATIENTS WITH MULTIPLE-SCLEROSIS AND OTHER NEUROLOGICAL DISEASES", Multiple sclerosis, 3(6), 1997, pp. 363-369

Abstract

Antibodies to on axolemma-enriched fraction (AEF) antigen have been detected in the cerebrospinal fluid (CSF) and serum of patients with Multiple Sclerosis (MS) using an enzyme-linked immunosorbent assay (ELISA). A marginal elevation (P < 0.08) of anti-AEF IgG was found in MS CSF when compared with OND samples. When CSF was diluted to a standardized IgG concentration, the anti-AEF IgG level in MS CSF was significantly elevated (P = 0.007) when compared to OND CSF. MS serum was also found to contain a significantly higher level (P < 0.001) of anti-AEF IgG when compared to OND serum using the ELISA technique.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 07/07/20 alle ore 21:15:25