Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
SYNTAXIN-10 - A MEMBER OF THE SYNTAXIN FAMILY LOCALIZED TO THE TRANS-GOLGI NETWORK
Autore:
TANG BL; LOW DYH; TAN AEH; HONG WJ;
Indirizzi:
INST MOL & CELL BIOL,MEMBRANE BIOL LAB,30 MED DR SINGAPORE 117609 SINGAPORE INST MOL & CELL BIOL,MEMBRANE BIOL LAB SINGAPORE 117609 SINGAPORE
Titolo Testata:
Biochemical and biophysical research communications
fascicolo: 2, volume: 242, anno: 1998,
pagine: 345 - 350
SICI:
0006-291X(1998)242:2<345:S-AMOT>2.0.ZU;2-5
Fonte:
ISI
Lingua:
ENG
Soggetto:
INTEGRAL MEMBRANE-PROTEIN; BREFELDIN-A; ORGANELLE STRUCTURE; VESICLES; TGN; ACTIVATION; RECEPTORS; MECHANISM; DOCKING; PATHWAY;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
28
Recensione:
Indirizzi per estratti:
Citazione:
B.L. Tang et al., "SYNTAXIN-10 - A MEMBER OF THE SYNTAXIN FAMILY LOCALIZED TO THE TRANS-GOLGI NETWORK", Biochemical and biophysical research communications, 242(2), 1998, pp. 345-350

Abstract

We have cloned a new member of the syntaxin family of proteins, designated human syntaxin 10 (hsyn10). The open reading frame encodes a polypeptide of 249 amino acids with potential coiled-coil domains and a carboxy-terminal hydrophobic tail. hsyn10 is particularly homologous tothe recently reported rat syntaxin 6 (about 60% identity). Northern blot analysis showed that the transcript is enriched in the heart, skeletal muscles and pancreas. indirect immunofluorescence studies using polyclonal antibodies raised against recombinant protein showed that the protein is localized to intracellular membrane structures, with perinuclear staining patterns colocalising well with the Golgi SNARE GS28. Morphological alterations of the staining pattern of the protein withbrefeldin A but not wortmannin treatment indicate that the protein islocalize to the trans-Golgi network. (C) 1998 Academic Press.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 20/09/20 alle ore 07:52:46