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Titolo:
RADIATION-THERAPY FOR BREAST-CANCER AND INCREASED RISK FOR ESOPHAGEAL-CARCINOMA
Autore:
AHSAN H; NEUGUT AI;
Indirizzi:
COLUMBIA UNIV,SCH PUBL HLTH,DIV EPIDEMIOL,600 W 168TH ST NEW YORK NY 10032 COLUMBIA UNIV COLL PHYS & SURG,DEPT MED,DIV ONCOL NEW YORK NY 10032
Titolo Testata:
Annals of internal medicine
fascicolo: 2, volume: 128, anno: 1998,
pagine: 114 - 117
SICI:
0003-4819(1998)128:2<114:RFBAIR>2.0.ZU;2-K
Fonte:
ISI
Lingua:
ENG
Soggetto:
LUNG-CANCER; TUMORS; CHEMOTHERAPY;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
23
Recensione:
Indirizzi per estratti:
Citazione:
H. Ahsan e A.I. Neugut, "RADIATION-THERAPY FOR BREAST-CANCER AND INCREASED RISK FOR ESOPHAGEAL-CARCINOMA", Annals of internal medicine, 128(2), 1998, pp. 114-117

Abstract

Background: Several case reports have suggested an association between radiation therapy for breast cancer and the subsequent occurrence ofesophageal carcinomas. Objective: To examine the association between radiation therapy for breast cancer and subsequent esophageal squamous-cell carcinomas and adenocarcinomas. Design: Population-based retrospective cohort study. Setting: Population-based U.S. cancer registries. Patients: 220 806 women in whom breast cancer was diagnosed between 1January 1973 and 31 December 1993; 1 216 853 person-years of follow-up. Measurements: Age- and period-adjusted standardized incidence ratioas a measure of relative risk for the second primary cancer. Results:In women who had received radiation therapy for breast cancer, the relative risk for esophageal squamous-cell carcinoma increased to 5.42 (95% CI, 2.33 to 10.68) and the relative risk for esophageal adenocarcinoma increased to 4.22 (CI, 0.47 to 15.25) 10 or more years after radiation therapy. No increased risk was seen for either type of carcinomaamong patients with breast cancer who did not receive radiation therapy. Conclusion: The risk for esophageal carcinoma is increased in women who receive radiation therapy for breast cancer.

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Documento generato il 03/12/20 alle ore 10:56:34