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Titolo:
HOMOTRANSPLANT OF PELVIC GANGLION INTO BLADDER WALL IN ADULT RATS
Autore:
GABELLA G; UVELIUS B;
Indirizzi:
UNIV COLL LONDON,DEPT ANAT,MORTIMER ST LONDON WC1E 6BT ENGLAND LUND UNIV,DEPT UROL LUND SWEDEN
Titolo Testata:
Neuroscience
fascicolo: 2, volume: 83, anno: 1998,
pagine: 645 - 653
SICI:
0306-4522(1998)83:2<645:HOPGIB>2.0.ZU;2-K
Fonte:
ISI
Lingua:
ENG
Soggetto:
INTRAMURAL NEURONS; PARKINSONS-DISEASE; URINARY-BLADDER; FEMALE RAT; TRANSPLANTATION; HISTOCHEMISTRY; OBSTRUCTION; SURVIVAL; CELLS;
Keywords:
PELVIC GANGLION; TRANSPLANT; URINARY BLADDER;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
20
Recensione:
Indirizzi per estratti:
Citazione:
G. Gabella e B. Uvelius, "HOMOTRANSPLANT OF PELVIC GANGLION INTO BLADDER WALL IN ADULT RATS", Neuroscience, 83(2), 1998, pp. 645-653

Abstract

In these experiments a large portion of the pelvic ganglion of adult female rats was transplanted into the wall of the urinary bladder of the same animals. The morphology and fine structure of the transplants were studied in whole-mounts and in sections for light and electron microscopy, from two days up to four months after operation. The generalarchitecture of the ganglion was preserved in all the transplants. The vascularization was re-established. Nerves grew out of the transplant and connections with the original intramural nerves of the bladder wall were established. All the synapses degenerated at the time of transplantation; new synapses began to reappear on the ganglion neurons inthe oldest transplants. Although some neurons in the transplant degenerated during the first few days, the majority of neurons survived forthe full length of the experiments (four months). Satellite glial cells and small intensely fluorescent cells had a similar structure and distribution as in control ganglia. The results show that the homotransplant of pelvic neurons into the bladder has a high rate of success, in terms of survival, maintenance of fine structure, growth and re-connections; these neurons of adult organisms display plastic and regenerative abilities. (C) 1997 IBRO. Published by Elsevier Science Ltd.

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Documento generato il 29/09/20 alle ore 20:35:42