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Titolo:
BREAST-CANCER RISK AND LIFETIME OCCUPATIONAL HISTORY - EMPLOYMENT IN PROFESSIONAL AND MANAGERIAL OCCUPATIONS
Autore:
PETRALIA SA; VENA JE; FREUDENHEIM JL; MARSHALL JR; MICHALEK A; BRASURE J; SWANSON M; GRAHAM S;
Indirizzi:
NCI,OCCUPAT EPIDEMIOL BRANCH,EXECUT PLAZA N,RM 418,6130 EXECUT BLVD BETHESDA MD 20892 SUNY BUFFALO,DEPT SOCIAL & PREVENT MED BUFFALO NY 14260 ARIZONA CANC CTR TUCSON AZ 00000 ROSWELL PK CANC INST BUFFALO NY 00000
Titolo Testata:
Occupational and environmental medicine
fascicolo: 1, volume: 55, anno: 1998,
pagine: 43 - 48
SICI:
1351-0711(1998)55:1<43:BRALOH>2.0.ZU;2-O
Fonte:
ISI
Lingua:
ENG
Soggetto:
RADIOLOGIC TECHNOLOGISTS; UNITED-STATES; MORTALITY; WOMEN; WORKERS; COHORT; HAIRDRESSERS; INDUSTRY; DENMARK; NURSES;
Keywords:
BREAST CANCER; OCCUPATION; EPIDEMIOLOGY; CASE-CONTROL;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
44
Recensione:
Indirizzi per estratti:
Citazione:
S.A. Petralia et al., "BREAST-CANCER RISK AND LIFETIME OCCUPATIONAL HISTORY - EMPLOYMENT IN PROFESSIONAL AND MANAGERIAL OCCUPATIONS", Occupational and environmental medicine, 55(1), 1998, pp. 43-48

Abstract

Objective-In this case-control study, occupational histories were used to assess the relation between risk of breast cancer and employment in professional and managerial occupations while adjusting for reproductive and other risk factors. Methods-Incident, primary, female cases of breast cancer diagnosed between 1986 and 1991, and randomly selected controls were interviewed to obtain detailed medical, reproductive, and occupational histories. Mantel-Haenszel crude odds ratios (OR) and95% confidence intervals (95% CIs) were used to estimate risk of breast cancer related to the job of longest duration. Unconditional logistic regression was used to estimate crude and adjusted ORs and 95% CIs associated with having ever been employed and duration of employment in a professional or managerial occupation. Results-A non-significant threefold increase in risk was found among premenopausal women whose major job was in the occupational category of precision production, craft, and repair (95% CI 0.90 to 20.35). No increase in risk was found for premenopausal women whose major job was a managerial or professionaloccupation. However, an inverse relation between risk of premenopausal breast cancer and having ever held a professional or managerial job was observed (OR 0.53, 95% CI 0.34 to 0.82). This relation was strongest for women who worked one to 10 years (OR 0.47, 95% CI 0.29 to 0.77). Postmenopausal breast cancer was not related to professional and managerial employment. Conclusions-In this population, employment in professional and managerial occupations is not associated with postmenopausal risk of breast cancer, but seems to be related to a reduction in risk of premenopausal breast cancer. Methodological limitations of thisstudy including response rates are discussed.

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Documento generato il 30/03/20 alle ore 10:08:33