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Titolo:
SOCIAL DEPRIVATION OF NEONATAL, ADOLESCENT, AND ADULT RATS HAS DISTINCT NEUROCHEMICAL AND BEHAVIORAL CONSEQUENCES
Autore:
HALL FS;
Indirizzi:
NIAAA,DICBR,CLIN STUDIES LAB BETHESDA MD 20892
Titolo Testata:
Critical reviews in neurobiology
fascicolo: 1-2, volume: 12, anno: 1998,
pagine: 129 - 162
SICI:
0892-0915(1998)12:1-2<129:SDONAA>2.0.ZU;2-N
Fonte:
ISI
Lingua:
ENG
Soggetto:
LONG-TERM ISOLATION; CORTICOSTEROID RECEPTOR-BINDING; INDUCED ADRENOCORTICAL-RESPONSE; NEGATIVE FEEDBACK SENSITIVITY; EARLY MATERNAL SEPARATION; ADRENAL STRESS RESPONSES; ISOLATION-REARED RATS; ELEVATED PLUS-MAZE; GROUP-HOUSED RATS; MALE WISTAR RATS;
Keywords:
SOCIAL ISOLATION; SOCIAL DEPRIVATION; MATERNAL DEPRIVATION; DOPAMINE; SEROTONIN; ANIMAL MODELS;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
264
Recensione:
Indirizzi per estratti:
Citazione:
F.S. Hall, "SOCIAL DEPRIVATION OF NEONATAL, ADOLESCENT, AND ADULT RATS HAS DISTINCT NEUROCHEMICAL AND BEHAVIORAL CONSEQUENCES", Critical reviews in neurobiology, 12(1-2), 1998, pp. 129-162

Abstract

This review examines the consequences of social deprivation on brain chemistry and behavior on rats. Although social deprivation produces wide-ranging behavioral and neurochemical effects, it appears that these effects are determined by a number of factors, the most critical factor being the age or developmental stage during the period of deprivation. Roughly, the effects examined in this review may be separated into three major developmental stages and each is related to deprivation of specific types of social interaction: preweaning/neonatal, postweaning/adolescent, and adult. The effects of social deprivation during each of these stages appears to be neurochemically and behaviorally specific. However, much of the research to date has failed to examine deprivation during specific stages, often combining deprivation of different types. Nonetheless, these modifications of experience produce animals of differing phenotypes, which could be characterized as pathological in nature in many instances, and may model particular aspects of human psychopathologies or perhaps the propensity to develop those phenotypic features.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 25/01/20 alle ore 19:47:34