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Titolo:
A RANDOMIZED TRIAL OF 3 IRON DEXTRAN INFUSION METHODS FOR ANEMIA IN EPO-TREATED DIALYSIS PATIENTS
Autore:
AUERBACH M; WINCHESTER J; WAHAB A; RICHARDS K; MCGINLEY M; HALL F; ANDERSON J; BRIEFEL G;
Indirizzi:
FRANKLIN SQ HOSP CTR,9000 FRANKLIN SQ DR BALTIMORE MD 21237 JOHNS HOPKINS BAYVIEW MED CTR BALTIMORE MD 00000 GEORGETOWN UNIV,MED CTR WASHINGTON DC 20007
Titolo Testata:
American journal of kidney diseases
fascicolo: 1, volume: 31, anno: 1998,
pagine: 81 - 86
SICI:
0272-6386(1998)31:1<81:ARTO3I>2.0.ZU;2-0
Fonte:
ISI
Lingua:
ENG
Soggetto:
RECOMBINANT-HUMAN-ERYTHROPOIETIN; STAGE RENAL-DISEASE; HEMODIALYSIS-PATIENTS; MAINTENANCE HEMODIALYSIS; SERUM FERRITIN; ABSORPTION; REDUCTION; OVERLOAD; THERAPY;
Keywords:
IRON; DEXTRAN; HEMODIALYSIS; ERYTHROPOIETIN; ANEMIA;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
30
Recensione:
Indirizzi per estratti:
Citazione:
M. Auerbach et al., "A RANDOMIZED TRIAL OF 3 IRON DEXTRAN INFUSION METHODS FOR ANEMIA IN EPO-TREATED DIALYSIS PATIENTS", American journal of kidney diseases, 31(1), 1998, pp. 81-86

Abstract

Forty-three hemodialysis patients receiving recombinant erythropoietin (rHuEPO, epoietin alpha) were randomized to receive intravenous irondextran as a total-dose infusion, 500-mg infusion to total dose, or 100-mg bolus to total dose, in each case during the dialysis procedure,The dose of iron dextran was calculated from the patient's existing hemoglobin to achieve a desired hemoglobin, Patients were eligible to receive intravenous iron dextran if they had a serum ferritin of less than or equal to 100 ng/mL or a serum ferritin of 100 to 200 ng/mL, along with a transferrin saturation of less than or equal to 19%. Patients were excluded if they had prior therapy with iron dextran, aluminum intoxication, or transfusion during the study. The time to the maximumhemoglobin, acute adverse reactions, and delayed adverse reactions were analyzed statistically, and no differences were seen in any of the three groups, Total dose intravenous iron dextran infusion is safe, convenient, less expensive, and as efficacious as divided-dose infusions. (C) 1998 by the National Kidney Foundation, Inc.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 04/12/20 alle ore 22:45:38