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Titolo:
STRUCTURAL-ANALYSIS OF DROSOPHILA-SUBOBSCURA GYPSY ELEMENTS (GYPSYDS)
Autore:
ALBEROLA TM; BORI L; DEFRUTOS R;
Indirizzi:
UNIV VALENCIA,FAC CIENCIAS BIOL,DEPT GENET,DR MOLINER 50 E-46100 VALENCIA SPAIN UNIV VALENCIA,FAC CIENCIAS BIOL,DEPT GENET E-46100 VALENCIA SPAIN
Titolo Testata:
Genetica
fascicolo: 1-3, volume: 100, anno: 1997,
pagine: 39 - 48
SICI:
0016-6707(1997)100:1-3<39:SODGE(>2.0.ZU;2-7
Fonte:
ISI
Lingua:
ENG
Soggetto:
TRANSPOSABLE GENETIC ELEMENT; REVERSE-TRANSCRIPTASE; INFECTIOUS RETROVIRUS; NUCLEOTIDE-SEQUENCE; MOBILE ELEMENTS; FLAMENCO GENE; RETROTRANSPOSON; MELANOGASTER; GENOME; DNA;
Keywords:
DROSOPHILA SUBOBSCURA; ENV PROTEIN; GYPSY; RETROTRANSPOSONS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
44
Recensione:
Indirizzi per estratti:
Citazione:
T.M. Alberola et al., "STRUCTURAL-ANALYSIS OF DROSOPHILA-SUBOBSCURA GYPSY ELEMENTS (GYPSYDS)", Genetica, 100(1-3), 1997, pp. 39-48

Abstract

The study of gypsy elements in Drosophila subobscura (gypsyDs) indicated that they are transcriptionally active and mobile. From the comparative analysis of a complete gypsyDs element with the canonical gypsy sequence from D. melanogaster (gypsyDm) it can be deduced that while the whole structure is maintained, the gypsyDs ORF3 encodes a non-functional Env protein. The PCR amplification and sequencing of the ORF3 from different laboratory strains and H271 clones show that all gypsyDs sequences studied have frame-shifting mutations in this region. These results support that gypsyDs elements lack functional Env proteins andconsequently they lack infective ability. In this way, it can be proposed that gypsyDs elements are degenerate forms of insect retroviruses. Heterogeneous results have been obtained in the study of the presence of gypsyDm sequences in different D. subobscura strains indicating that these sequences are unstable in this species.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 30/11/20 alle ore 00:46:59