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Titolo:
KINETICS OF ACTIVE-TRANSPORT IN BIOLOGICAL-MEMBRANES - ROLE OF BARRIER FLUCTUATIONS
Autore:
FULINSKI A;
Indirizzi:
JAGIELLONIAN UNIV,M SMOLUCHOWSKI INST PHYS,REYMONTA 4 PL-30059 KRAKOWPOLAND
Titolo Testata:
Polish Journal of Chemistry
fascicolo: 12, volume: 71, anno: 1997,
pagine: 1680 - 1698
SICI:
0137-5083(1997)71:12<1680:KOAIB->2.0.ZU;2-6
Fonte:
ISI
Lingua:
ENG
Soggetto:
NONLINEAR CHEMICAL-KINETICS; OSCILLATING ELECTRIC-FIELD; EXTERNAL DISTURBANCES; TRANSITION RATES; NOISE; ACTIVATION; SYSTEMS; EQUATIONS; PROTEINS; ESCAPE;
Keywords:
FLUCTUATIONS; ACTIVE TRANSPORT; MEMBRANE POTENTIAL; KINETICS; MODEL SIMULATION;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
37
Recensione:
Indirizzi per estratti:
Citazione:
A. Fulinski, "KINETICS OF ACTIVE-TRANSPORT IN BIOLOGICAL-MEMBRANES - ROLE OF BARRIER FLUCTUATIONS", Polish Journal of Chemistry, 71(12), 1997, pp. 1680-1698

Abstract

The role of barrier fluctuations in the membrane enzymatic processes,among others in the active transport of ions through cell membranes is examined. Membrane electric potential plays the role of a barrier height (activation energy)for enzymes embedded in the cell membrane. This barrier height can be modulated either by internal fluctuations at by superimposed from without external electrical fields, either random or periodic. Measurements of the changes in reaction yield, or in ionic currents, governed by these enzymes (ionic pumps) can be used as tools for determining the parameters describing enzymatic action. Barrierfluctuations can change considerably the yield, including the inversion of the direction of transmembrane currents.

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Documento generato il 26/11/20 alle ore 18:54:47