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Titolo:
FAILURE OF THE HONG-KONG CRITERIA TO PREDICT THE SEVERITY OF ACUTE-PANCREATITIS
Autore:
HEATH DI; MENG WCS; ANDERSON JH; LEUNG KL; LAU WY; LI AKC;
Indirizzi:
CHINESE UNIV HONG KONG,PRINCE WALES HOSP,DEPT SURG SHATIN NEW TERRITORIES HONG KONG CHINESE UNIV HONG KONG,PRINCE WALES HOSP,DEPT SURG SHATIN NEW TERRITORIES HONG KONG
Titolo Testata:
International journal of pancreatology
fascicolo: 3, volume: 22, anno: 1997,
pagine: 201 - 206
SICI:
0169-4197(1997)22:3<201:FOTHCT>2.0.ZU;2-E
Fonte:
ISI
Lingua:
ENG
Soggetto:
C-REACTIVE PROTEIN; SCORING SYSTEMS; APACHE-II;
Keywords:
ACUTE PANCREATITIS; SEVERITY PREDICTION; GLASGOW SCORE; RANSON SCORE; HONG KONG CRITERIA;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
19
Recensione:
Indirizzi per estratti:
Citazione:
D.I. Heath et al., "FAILURE OF THE HONG-KONG CRITERIA TO PREDICT THE SEVERITY OF ACUTE-PANCREATITIS", International journal of pancreatology, 22(3), 1997, pp. 201-206

Abstract

Conclusion. The results of the present study demonstrate that the HK criteria do not provide effective prediction of severity. Background. Fan et al. (1) have reported previously that a blood urea (BU) >7.4 mmol/L and/or glucose (BG) >11 mmol/L at the time of admission to hospital detects a severe attack of acute pancreatitis with a sensitivity of76% and specificity of 75%. However, a similar study conducted in theWest of Scotland did not confirm these findings (sensitivity 33% and specificity 83%). The reason underlying this discrepancy in predictionis unclear, but it may be because of differences in the nature of acute pancreatitis between Asian and Western populations. Aims. In this study we examined the predictive ability of the Hong Kong (HK) criteriain a patient population similar to that studied by Fan et al. Patients and Methods. A consecutive series of 130 patients experienced 135 attacks of acute pancreatitis, One-hundred-and-four (77%) attacks were mild and 31 (23%) severe (including 12 [9.0%] deaths). Eighty-nine (66%) episodes had a biliary etiology. In 19 (14%) of these episodes, the gallstones had a primary ductal origin being associated with recurrentpyogenic cholangitis. Results. Median admission BU concentrations were 5.2 mmol/L (range 3.6-32.1 mmol/L) for the mild group and 7.6 mmol/L(range 3.6-28.8 mmol/L) for the severe group. Corresponding values ofBG were 7.1 mmol/L (range 2.1-17.9 mmol/L) and 8.4 mmol/L (range 3.6-28.8 mmol/L), respectively. Differences in admission BU concentrationsbetween patients with mild and severe episodes were significant (p = 0.0001). However, differences in BG concentrations were not (p = 0.16). In the severe group, 14 patients had BU and four patients BG concentrations above the cut-off values. The HK criteria predicted severe acute pancreatitis with a sensitivity of 52% and specificity of 80%. These results compare with values of 79 and 56% for the Ranson criteria and 83 and 60% for the Glasgow score. The best prediction was provided by the APACHE II score 24 h post admission (sensitivity 79%, specificity 82%).

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 10/07/20 alle ore 12:19:40