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Titolo:
EFFECT OF EXPERIMENTAL DIABETES ON MONOAMINE-OXIDASE ACTIVITY FROM DISCRETE AREAS OF RAT-BRAIN - RELATIONSHIP WITH DIABETES-ASSOCIATED REPRODUCTIVE FAILURE
Autore:
LAKHMAN SS; KAUR G;
Indirizzi:
GURU NANAK DEV UNIV,DEPT BIOTECHNOL,NEUROCHEM & NEUROENDOCRINOL LAB AMRITSAR 143005 PUNJAB INDIA GURU NANAK DEV UNIV,DEPT BIOTECHNOL,NEUROCHEM & NEUROENDOCRINOL LAB AMRITSAR 143005 PUNJAB INDIA
Titolo Testata:
Molecular and cellular biochemistry
fascicolo: 1-2, volume: 177, anno: 1997,
pagine: 15 - 20
SICI:
0300-8177(1997)177:1-2<15:EOEDOM>2.0.ZU;2-Z
Fonte:
ISI
Lingua:
ENG
Soggetto:
LUTEINIZING-HORMONE; NERVOUS-SYSTEM; GROWTH-FACTORS; INSULIN; METABOLISM; CATECHOLAMINES; HYPOTHALAMUS; MELLITUS; REGIONS; RELEASE;
Keywords:
DIABETES; MONOAMINE OXIDASE; REPRODUCTIVE FAILURE; MONOAMINES; BRAIN; INSULIN; NEUROENDOCRINE REGULATION; GONADOTROPINS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
38
Recensione:
Indirizzi per estratti:
Citazione:
S.S. Lakhman e G. Kaur, "EFFECT OF EXPERIMENTAL DIABETES ON MONOAMINE-OXIDASE ACTIVITY FROM DISCRETE AREAS OF RAT-BRAIN - RELATIONSHIP WITH DIABETES-ASSOCIATED REPRODUCTIVE FAILURE", Molecular and cellular biochemistry, 177(1-2), 1997, pp. 15-20

Abstract

The effect of alloxan-induced diabetes was studied on the activity ofmonoamine oxidase (MAO), the oxidative deaminating enzyme of monoamine neurotransmitters. MAO wa's assayed from discrete brain regions likemedial preoptic area and median eminence - arcuate region of hypothalamus, septum, amygdala, thalamus, hippocampus, pens and medulla. In all these areas studied, the induction of diabetes resulted in significant increase in MAO activity at 3, 8, 15 and 28 day intervals, whereas,the treatment of diabetic rats with insulin led to recovery in the enzyme activity. Blood glucose levels increased significantly after induction of diabetes and the recovery was seen after insulin treatment. These data suggest the involvement of MAO in diabetes associated alterations in physiological and endocrinological disorders.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 29/11/20 alle ore 16:13:53