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Titolo:
NEUROPEPTIDE-Y AND PEPTIDE YY IMMUNOREACTIVITIES IN THE PANCREAS OF VARIOUS VERTEBRATES
Autore:
DING WG; KIMURA H; FUJIMURA M; FUJIMIYA M;
Indirizzi:
SHIGA UNIV MED SCI,DEPT ANAT SHIGA 52021 JAPAN SHIGA UNIV MED SCI,DEPT ANAT SHIGA 52021 JAPAN SHIGA UNIV MED SCI,INST MOL NEUROBIOL SHIGA 52021 JAPAN SHIGA UNIV MED SCI,DEPT PHYSIOL SHIGA 52021 JAPAN SHIGA UNIV MED SCI,DEPT SURG SHIGA 52021 JAPAN
Titolo Testata:
Peptides
fascicolo: 10, volume: 18, anno: 1997,
pagine: 1523 - 1529
SICI:
0196-9781(1997)18:10<1523:NAPYII>2.0.ZU;2-5
Fonte:
ISI
Lingua:
ENG
Soggetto:
IN-SITU HYBRIDIZATION; ENDOCRINE PANCREAS; INSULIN-SECRETION; RAT PANCREAS; DEXAMETHASONE TREATMENT; CELLS; LOCALIZATION; POLYPEPTIDE; GUT; GLUCAGON;
Keywords:
NPY; PYY; ENDOCRINE; PANCREATIC; VERTEBRATE; NERVE;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
34
Recensione:
Indirizzi per estratti:
Citazione:
W.G. Ding et al., "NEUROPEPTIDE-Y AND PEPTIDE YY IMMUNOREACTIVITIES IN THE PANCREAS OF VARIOUS VERTEBRATES", Peptides, 18(10), 1997, pp. 1523-1529

Abstract

NPY-like immunoreactivity was observed in nerve fibers and endocrine cells in pancreas of all species examined except the eel, which showedno NPY innervation. The density of NPY-positive nerve fibers was higher in mammals than in the lower vertebrates. These nerve fibers were distributed throughout the parenchyma, and were particularly associatedwith the pancreatic duct and vascular walls. In addition, the densityof NPY-positive endocrine cells was found to be higher in lower vertebrates than mammals; in descending order; eel = turtle = chicken > bullfrog > mouse = rat = human = guinea pig = dog. These NPY-positive cells in the eel and certain mammals tended to be localized throughout the islet region, whereas in the turtle and chicken they were mainly scattered in the exocrine region. PYY-immunoreactivity was only present in the pancreatic endocrine cells of all species studied, and localizedsimilarly to NPY. Thus these two peptides may play endocrine or paracrine roles in the regulation of islet hormone secretion in various vertebrate species. (C) 1997 Elsevier Science Inc.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 04/04/20 alle ore 11:16:13