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Titolo:
CHANGES IN NITRITE AND NITRATE (NO2- NO3-) LEVELS IN CEREBROSPINAL-FLUID OF PATIENTS WITH MULTIPLE-SCLEROSIS/
Autore:
YAMASHITA T; ANDO Y; OBAYASHI K; UCHINO M; ANDO M;
Indirizzi:
UMEA UNIV,DEPT INTERNAL MED S-90187 UMEA SWEDEN KUMAMOTO UNIV,SCH MED,DEPT INTERNAL MED 1 KUMAMOTO 860 JAPAN KUMAMOTO UNIV,SCH MED,DEPT NEUROL KUMAMOTO 860 JAPAN
Titolo Testata:
Journal of the neurological sciences
fascicolo: 1, volume: 153, anno: 1997,
pagine: 32 - 34
SICI:
0022-510X(1997)153:1<32:CINAN(>2.0.ZU;2-Z
Fonte:
ISI
Lingua:
ENG
Soggetto:
OXIDE SYNTHASE; BRAINS;
Keywords:
MULTIPLE SCLEROSIS; NITRIC OXIDE SYNTHASE; NO2-/NO3-; CEREBROSPINAL FLUID; METHYLPREDONISOLONE; ACTIVITY;
Tipo documento:
Article
Natura:
Periodico
Citazioni:
8
Recensione:
Indirizzi per estratti:
Citazione:
T. Yamashita et al., "CHANGES IN NITRITE AND NITRATE (NO2- NO3-) LEVELS IN CEREBROSPINAL-FLUID OF PATIENTS WITH MULTIPLE-SCLEROSIS/", Journal of the neurological sciences, 153(1), 1997, pp. 32-34

Abstract

To compare the change in nitric oxide (NO) metabolism in patients with multiple sclerosis (MS) in different clinical stages, such as exacerbation, remission, and 1-2 months after methylpredonisolone administration, we measured the nitrite and nitrate (NO2-/NO3-) levels in the cerebrospinal fluid (CSF). In the extreme stage of MS exacerbation, those levels were remarkably elevated, compared with those both after methylpredonisolone administration and remission. These results suggest that, in addition to MRI study, measurement of NO metabolites in the CSFmay give information to help us understand the activity of MS and effect of drugs on the disease. (C) 1997 Elsevier Science B.V.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 12/07/20 alle ore 12:28:05