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Titolo:
TOXIN INVOLVEMENT IN STAPHYLOCOCCAL SCALDED SKIN SYNDROME
Autore:
LINA G; GILLET Y; VANDENESCH F; JONES ME; FLORET D; ETIENNE J;
Indirizzi:
FAC MED,BACTERIOL LAB,CTR NATL REFERENCE STAPHYLOCOQUES,RUE GUILLAUMEPARADIN F-69372 LYON 08 FRANCE HOP EDOUARD HERRIOT,UNITE URGENCE & REANIMAT PEDIAT LYON FRANCE UNIV UTRECHT HOSP,EIJKMAN WINKLER INST CLIN MICROBIOL UTRECHT NETHERLANDS
Titolo Testata:
Clinical infectious diseases
fascicolo: 6, volume: 25, anno: 1997,
pagine: 1369 - 1373
SICI:
1058-4838(1997)25:6<1369:TIISSS>2.0.ZU;2-F
Fonte:
ISI
Lingua:
ENG
Soggetto:
LYMPHOCYTE-ASSOCIATED ANTIGEN; SHOCK SYNDROME TOXIN-1; EXFOLIATIVE TOXIN; AUREUS; ENTEROTOXINS; SUPERANTIGENS; EXPRESSION; SPECTRUM; DISEASE; ADULTS;
Tipo documento:
Article
Natura:
Periodico
Citazioni:
41
Recensione:
Indirizzi per estratti:
Citazione:
G. Lina et al., "TOXIN INVOLVEMENT IN STAPHYLOCOCCAL SCALDED SKIN SYNDROME", Clinical infectious diseases, 25(6), 1997, pp. 1369-1373

Abstract

The production of staphylococcal exfoliative toxin A (ETA) and toxin B (ETB), toxic shock syndrome toxin (TSST-1), and enterotoxins A-E wasanalyzed in 60 Staphylococcus aureus strains isolated from children with scalded skin syndrome (15 with generalized exfoliative syndrome, 28 with bullous impetigo, and 17 with staphylococcal scarlet fever). All strains isolated from patients with generalized exfoliative syndromeor bullous impetigo produced ETA and/or ETB and caused a Nikolsky's sign when injected subcutaneously into newborn mice. In contrast, exfoliative toxin was detected in an S. aureus strain from only one of 17 cases of staphylococcal scarlet fever; the 16 other S. aureus strains produced TSST-1 and/or an enterotoxin. In conclusion, enterotoxins or TSST-1 are more frequently associated with staphylococcal scarlet feverthan are exfoliative toxins. Hence staphylococcal scarlet fever may well represent an abortive form of toxic shock syndrome rather than a milder form of staphylococcal scalded skin syndrome.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 30/11/20 alle ore 16:21:51