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Titolo:
MEDICINAL FOODSTUFFS - X - STRUCTURES OF NEW TRITERPENE GLYCOSIDES, GYMNEMOSIDE-C, GYMNEMOSIDE-D, GYMNEMOSIDE-E, AND GYMNEMOSIDE-F, FROM THE LEAVES OF GYMNEMA-SYLVESTRE R. BR - INFLUENCE OF GYMNEMA GLYCOSIDES ON GLUCOSE-UPTAKE IN RAT SMALL-INTESTINAL FRAGMENTS
Autore:
YOSHIKAWA M; MURAKAMI T; MATSUDA H;
Indirizzi:
KYOTO PHARMACEUT UNIV,YAMASHIMA KU,5 NAKAUCHI CHO KYOTO 607 JAPAN
Titolo Testata:
Chemical and Pharmaceutical Bulletin
fascicolo: 12, volume: 45, anno: 1997,
pagine: 2034 - 2038
SICI:
0009-2363(1997)45:12<2034:MF-X-S>2.0.ZU;2-R
Fonte:
ISI
Lingua:
ENG
Soggetto:
ARALIA-ELATA SEEM; HYPOGLYCEMIC ACTIVITY; BIOACTIVE SAPONINS; ETHANOL ABSORPTION; ACID; CONSTITUENTS; ROOT; IV;
Keywords:
GYMNEMOSIDE; GYMNEMA SYLVESTRE; GLUCOSE UPTAKE INHIBITOR; BIOACTIVE SAPONIN; GYMNEMIC ACID; MEDICINAL FOODSTUFF;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
22
Recensione:
Indirizzi per estratti:
Citazione:
M. Yoshikawa et al., "MEDICINAL FOODSTUFFS - X - STRUCTURES OF NEW TRITERPENE GLYCOSIDES, GYMNEMOSIDE-C, GYMNEMOSIDE-D, GYMNEMOSIDE-E, AND GYMNEMOSIDE-F, FROM THE LEAVES OF GYMNEMA-SYLVESTRE R. BR - INFLUENCE OF GYMNEMA GLYCOSIDES ON GLUCOSE-UPTAKE IN RAT SMALL-INTESTINAL FRAGMENTS", Chemical and Pharmaceutical Bulletin, 45(12), 1997, pp. 2034-2038

Abstract

Following the characterization of gymnemosides-a and -b, new triterpene glycosides, gymnemosides-c, -d, -e, and -f, were isolated from the leaves of Gymnema (G.) sylvestre R. BR. Their chemical structures wereelucidated an the basis of chemical and physicochemical evidence as follows: 21-O-benzoyl-28-O-acetylgymnemagenin 3-O-beta-D-glucopyranosiduronic acid (gymnemoside-c), 23-O-[beta-D-xylopyranosyl (1-->6)-beta-D-glucopyranosyl ta-D-glucopyranosyl]gymnestrogenin(gymnemoside-d), beta-D-glucopyranosyl]-28-O-[beta-D-glucopyranosyl (1-->6)-beta-D-glucopyranosyl] 23-hydroxylongispinogenin (gymnemoside-e), 23-O-[beta-D-glucopyranosyl (1-->6)-beta-D-glucopyranosyl beta-D-glucopyranosyl]-28-O-[beta-D-glucopyranosyl (1-->6)-beta-D-glucopyranosyl] 3 beta,16 beta,23,28-tetrahydroxyolean-18-ene (gymnemoside-f). The inhibitory effects ofgymnemosides-c, -d, -e, and -f and principal triterpene glycosides from G. sylvestre on glucose uptake in rat small intestinal fragments were examined, and gymnemic acids II, III, and IV, gymnemasaponin V, andgymnemoside-f were found to exhibit the inhibitory activity.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 30/09/20 alle ore 12:43:02