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Titolo:
NONDESTRUCTIVE DETERMINATION OF ILIAC CREST CANCELLOUS BONE STRENGTH BY PQCT
Autore:
EBBESEN EN; THOMSEN JS; MOSEKILDE L;
Indirizzi:
ODENSE UNIV HOSP,DEPT ENDOCRINOL,KLOVERVAENGET 4 DK-5000 ODENSE C DENMARK AARHUS UNIV,INST ANAT,DEPT CELL BIOL DK-8000 AARHUS DENMARK
Titolo Testata:
Bone
fascicolo: 6, volume: 21, anno: 1997,
pagine: 535 - 540
SICI:
8756-3282(1997)21:6<535:NDOICC>2.0.ZU;2-V
Fonte:
ISI
Lingua:
ENG
Soggetto:
QUANTITATIVE COMPUTED-TOMOGRAPHY; VERTEBRAL TRABECULAR BONE; COMPRESSIVE STRENGTH; LUMBAR SPINE; POSTMENOPAUSAL OSTEOPOROSIS; MECHANICAL-PROPERTIES; NORMAL INDIVIDUALS; ASH DENSITY; MASS; BEHAVIOR;
Keywords:
ILIAC CREST BONE BIOPSY; CANCELLOUS BONE; BONE STRENGTH; ASH DENSITY; PERIPHERAL QUANTITATIVE COMPUTED TOMOGRAPHY (PQCT); BIOMECHANICS;
Tipo documento:
Article
Natura:
Periodico
Citazioni:
37
Recensione:
Indirizzi per estratti:
Citazione:
E.N. Ebbesen et al., "NONDESTRUCTIVE DETERMINATION OF ILIAC CREST CANCELLOUS BONE STRENGTH BY PQCT", Bone, 21(6), 1997, pp. 535-540

Abstract

The close relationship between apparent bone density and compressive strength is well established, In clinical situations, histomorphometryand determination of the compressive strength on bone biopsies are destructive methods and require two separate biopsies from each patient,The aim of this study was to evaluate whether volumetric bone densitymeasured ba peripheral quantitative computed tomography (pQCT) could be used as a nondestructive method for estimating trabecular bone strength of iliac crest bone biopsies, thereby allowing the same biopsy tobe used for subsequent histomorphometry. Materials consisted of trabecular bone samples prepared from unilateral transiliac crest bone samples obtained at autopsy [total 95 specimens; 41 females (21-90 years) and 51 males (23-87 years)], From these, the apparent density of the cancellous bone was evaluated by pQCT in a 1-mm-thick slice in the middle of the biopsy and also by ash density measurement, Bone strength was measured by compression test, A strong power relationship was found between density measured by pQCT and compressive strength (r = 0.93, p< 0.00001), Likewise, there was a strong power relationship between ash density and compressive strength (r = 0.97, p < 0.00001). A linear correlation was found between pQCT measurement and ash density (r 0.98, p < 0.00001), indicating a very high accuracy for the pQCT measurement. In conclusion, pQCT provides a very good estimate of cancellous bone strength, This nondestructive assessment of strength of iliac crestbone biopsies thereby enables biomechanical information as well as histomorphometric measurements to be obtained from the same biopsy. (C) 1997 by Elsevier Science Inc. All rights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 24/11/20 alle ore 08:32:14