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Titolo:
EFFECT OF EXERCISE AND EXOGENOUS GLUCOCORTICOID ON SERUM LEVEL OF INTACT PARATHYROID-HORMONE
Autore:
TSAI KS; LIN JC; CHEN CK; CHENG WC; YANG CH;
Indirizzi:
NATL TAIPEI TEACHERS COLL,DEPT EDUC PHYS,134 SECT 2 HO PING E RD TAIPEI TAIWAN NATL TAIPEI TEACHERS COLL,DEPT EDUC PHYS TAIPEI TAIWAN NATL TAIWAN NORMAL UNIV,DEPT EDUC PHYS TAIPEI TAIWAN NATL TAIWAN UNIV,COLL MED,DEPT LAB MED TAIPEI 10764 TAIWAN
Titolo Testata:
International journal of sports medicine
fascicolo: 8, volume: 18, anno: 1997,
pagine: 583 - 587
SICI:
0172-4622(1997)18:8<583:EOEAEG>2.0.ZU;2-I
Fonte:
ISI
Lingua:
ENG
Soggetto:
CALCIUM; CALCITONIN; RESPONSES; STRESS;
Keywords:
EXERCISE; GLUCOCORTICOID; PARATHYROID HORMONE;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
27
Recensione:
Indirizzi per estratti:
Citazione:
K.S. Tsai et al., "EFFECT OF EXERCISE AND EXOGENOUS GLUCOCORTICOID ON SERUM LEVEL OF INTACT PARATHYROID-HORMONE", International journal of sports medicine, 18(8), 1997, pp. 583-587

Abstract

Most previous studies suggest that physical exercise, or physiological response to exercise such as cortisol and adrenaline secretion regulate parathyroid hormone (PTH) secretion in humans. To investigate the effects and possible interaction of exercise and excessive glucocorticoid on PTH secretion, we examined the serum of levels of intact-PTH, cortisol, adrenocorticotrophic hormone (ACTH), calcium, magnesium and phosphorus before and during one-hour of bicycle-ergometric exercise at60% of maximal oxygen uptake. These exercise tests were performed on eight Chinese male volunteers aged between 20 and 25 years, once with and once without pretreatment with 0.5 mg of dexamethasone taken orally 9.5 hours in advance, The results showed that dexamethasone pretreatment significantly lowered basal levels of cortisol and ACTH, but intact PTH did not change. After 60 minutes of bicycling, intact PTH levelincreases by 50% of baseline both with and without dexamethasone pretreatment. Serum levels of calcium, corrected for changes in serum albumin concentration, phosphorus and magnesium also increased in both cases. This study demonstrated an increase of intact-PTH with exercise which was not associated with hypocalcemia or hypomagnesemia, and was not altered in the presence of mild exogenous glucocorticoid excess and suppressed endogenous cortisol secretion.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 03/12/20 alle ore 05:47:43