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Titolo:
FACILITATION AND INHIBITION OF THE ACOUSTIC STARTLE REFLEX IN THE RATAFTER A MOMENTARY INCREASE IN BACKGROUND-NOISE LEVEL
Autore:
ISON JR; TAYLOR MK; BOWEN GP; SCHWARZKOPF SB;
Indirizzi:
UNIV ROCHESTER,DEPT BRAIN & COGNIT SCI,MELIORA HALL ROCHESTER NY 14627
Titolo Testata:
Behavioral neuroscience
fascicolo: 6, volume: 111, anno: 1997,
pagine: 1335 - 1352
SICI:
0735-7044(1997)111:6<1335:FAIOTA>2.0.ZU;2-L
Fonte:
ISI
Lingua:
ENG
Soggetto:
TEMPORAL RESOLUTION; AUDITORY FUNCTION; GAPS; AMPLITUDE; STIMULI;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
44
Recensione:
Indirizzi per estratti:
Citazione:
J.R. Ison et al., "FACILITATION AND INHIBITION OF THE ACOUSTIC STARTLE REFLEX IN THE RATAFTER A MOMENTARY INCREASE IN BACKGROUND-NOISE LEVEL", Behavioral neuroscience, 111(6), 1997, pp. 1335-1352

Abstract

Small increments in background noise were shown to increase the amplitude of a subsequently elicited acoustic startle reflex (ASR) in rats by as much as 100% under optimal conditions. Increment lead time (5-160 ms) and level (1.5-15 dB), initial noise level (30-70 dB), startle level (95-125 dB), number of test days (1-5), and drug condition (diazepam or saline ip) were varied in 6 experiments. Prepulse facilitation (PPF), measured by difference scores, was greatest for intermediate increments (3 dB) and lead times (20-40 ms) and was replaced by prepulseinhibition (PPI) for higher values, especially in the later test days. Diazepam reduced baseline ASR and diminished PPI, but it did not affect PPF. These data argue against hypotheses that attribute PPF of this sort to either temporal integration within the ASR pathways or to the elicitation of a nonspecific arousal reaction by the prepulse.

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Documento generato il 10/07/20 alle ore 01:50:22