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Titolo:
OPTICAL IMAGING OF DYNAMIC HORIZONTAL SPREAD OF EXCITATION IN RAT AUDITORY-CORTEX SLICES
Autore:
KUBOTA M; SUGIMOTO S; HORIKAWA J; NASU M; TANIGUCHI I;
Indirizzi:
TOKYO MED & DENT UNIV,MED RES INST,DEPT NEUROPHYSIOL,2-3-10 KANDA SURUGADAI TOKYO 101 JAPAN
Titolo Testata:
Neuroscience letters
fascicolo: 2-3, volume: 237, anno: 1997,
pagine: 77 - 80
SICI:
0304-3940(1997)237:2-3<77:OIODHS>2.0.ZU;2-8
Fonte:
ISI
Lingua:
ENG
Soggetto:
ELECTRICAL-ACTIVITY; REPRESENTATION; FREQUENCY;
Keywords:
OPTICAL IMAGING; AUDITORY CORTEX; SPATIOTEMPORAL PATTERN; HORIZONTAL PROPAGATION; VOLTAGE-SENSITIVE DYE; GLUTAMATE RECEPTORS; SLICE PREPARATION;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
15
Recensione:
Indirizzi per estratti:
Citazione:
M. Kubota et al., "OPTICAL IMAGING OF DYNAMIC HORIZONTAL SPREAD OF EXCITATION IN RAT AUDITORY-CORTEX SLICES", Neuroscience letters, 237(2-3), 1997, pp. 77-80

Abstract

Optical recordings using a voltage-sensitive dye (RH482) were conducted in brain slice preparations to investigate spatiotemporal patterns of excitation in the rat auditory cortex. Electrical stimulation of the border between the white matter and layer VI evoked vertical as wellas horizontal spreading responses. While Velocities of vertical and horizontal propagation of excitation were similar to those reported in non-disinhibited preparations, the horizontal propagation was widespread and strong especially in layers II/III in auditory cortex slices. This horizontal spread was blocked by 6-cyano-7-nitroquinoxaline-2,3-dione (CNQX) but not by D-2-amino-5-phosphonopentanoic acid (D-AP5). These results suggest that the horizontal responses, especially in layersII/III, are prominent and are mediated primarily by non-N-methyl-D-aspartic acid (NMDA) receptors in the auditory cortex. (C) 1997 ElsevierScience Ireland Ltd.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 07/04/20 alle ore 23:14:26