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Titolo:
THE RATION BETWEEN CARCINOMA ANTIGEN-125 LEVELS IN THE SEMINAL PLASMAAND SERUM MAY BE A MARKER FOR FERTILIZATION IN INTRACYTOPLASMIC SPERMINJECTION
Autore:
GEVA E; ARAVA J; LERNERGEVA L; HAREUVENI M; LESSING JB; BALLAS S; AMIT A;
Indirizzi:
TEL AVIV SOURASKY MED CTR,LIS MATERN HOSP,IVF UNIT,POB 7079 IL-61070 TEL AVIV ISRAEL TEL AVIV UNIV,SACKLER FAC MED IL-69978 TEL AVIV ISRAEL
Titolo Testata:
Fertility and sterility
fascicolo: 6, volume: 68, anno: 1997,
pagine: 1120 - 1124
SICI:
0015-0282(1997)68:6<1120:TRBCAL>2.0.ZU;2-Y
Fonte:
ISI
Lingua:
ENG
Soggetto:
OVARIAN-CANCER; MONOCLONAL-ANTIBODY; CA-125; RATES;
Keywords:
CARCINOMA ANTIGEN-125; FERTILIZATION; ICSI; IVF; SEMINAL PLASMA;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
19
Recensione:
Indirizzi per estratti:
Citazione:
E. Geva et al., "THE RATION BETWEEN CARCINOMA ANTIGEN-125 LEVELS IN THE SEMINAL PLASMAAND SERUM MAY BE A MARKER FOR FERTILIZATION IN INTRACYTOPLASMIC SPERMINJECTION", Fertility and sterility, 68(6), 1997, pp. 1120-1124

Abstract

Objective: To assess the relationship between tumor marker carcinoma antigen-125 levels in seminal plasma and serum and fertilization ratesin an IVF program, using intracytoplasmic sperm injection (ICSI). Design: A prospective study. Setting: IVF Unit, Lis Maternity Hospital, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel. Patient(s): Twenty-five infertile patients with severe oligo-terato-asthenospermia syndrome and 25 fertile male donors. Intervention(s): None. Main Outcome Measure(s): Sevum and seminal plasma carcinoma antigen-125 concentrationsand fertilization rate per cycle. Result(s): In the infer tile group,the seminal plasma carcinoma antigen-125 levels ranged from 22.0 to 1,284.0 U/mL (mean level +/- SD, 229.9 +/- 274.2 U/mL). In the normospermic fertile male donors, the seminal plasma carcinoma antigen-125 concentrations ranged from 12.2 to 336.7 U/mL (mean level +/- SD, 110.1 +/- 91.6 U/mL). This difference was statistically significant. The mean+/- SD ratio between the seminal plasma/serum carcinoma antigen-125 levels differed significantly between the infertile group (47.9 +/- 61.3) and the fertile male donors (5.7 +/- 3.5). In the infertile group, the ratio between the seminal plasma/serum carcinoma antigen-125 levels was found to be negatively correlated with the oocyte fertilization rate. Conclusion(s): The ratio between carcinoma antigen-125 levels inthe seminal plasma and serum may be an indirect marker for male infertility and fertilization rate in IVF treatment using ICSI. (C) 1997 byAmerican Society for Reproductive Medicine.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 03/12/20 alle ore 06:10:15