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Titolo:
FCRN - THE MHC CLASS I-RELATED RECEPTOR THAT IS MORE THAN AN IGG TRANSPORTER
Autore:
GHETIE V; WARD ES;
Indirizzi:
UNIV TEXAS,SW MED CTR,CTR CANC IMMUNOBIOL,5323 HARRY HINES BLVD DALLAS TX 75235 UNIV TEXAS,SW MED CTR,DEPT MICROBIOL DALLAS TX 75235
Titolo Testata:
Immunology today
fascicolo: 12, volume: 18, anno: 1997,
pagine: 592 - 598
SICI:
0167-5699(1997)18:12<592:F-TMCI>2.0.ZU;2-U
Fonte:
ISI
Lingua:
ENG
Soggetto:
T-CELL RECEPTOR; IMMUNOGLOBULIN-G; HUMAN PLACENTA; NEONATAL RAT; CRYSTAL-STRUCTURE; COMPLEX; MOLECULE; MICE; LOCALIZATION; BINDING;
Tipo documento:
Review
Natura:
Periodico
Citazioni:
49
Recensione:
Indirizzi per estratti:
Citazione:
V. Ghetie e E.S. Ward, "FCRN - THE MHC CLASS I-RELATED RECEPTOR THAT IS MORE THAN AN IGG TRANSPORTER", Immunology today, 18(12), 1997, pp. 592-598

Abstract

Recent data have indicated that the major histocompatibility complex (MHC) class I-related receptor FcRn plays a role in regulating serum IgG levels, in addition to transferring maternal IgGs across the rodentneonatal gut. The isolation of a human homolog of FcRn from placenta suggests that the studies in rodents have relevance to understanding similar processes in humans. This has implications for the engineering of improved antibodies for therapy.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 27/11/20 alle ore 21:33:49