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Titolo:
MODULATION OF PULMONARY ARTERIAL INPUT IMPEDANCE DURING TRANSITION FROM INSPIRATION TO EXPIRATION
Autore:
CASTIGLIONI P; TOMMASINI R; MORPURGO M; DIRIENZO M;
Indirizzi:
FDN PRO JUVENTUTE DON GNOCCHI,LAB RIC CARDIOVASC,CTR BIOINGN,LARC,VIAGOZZADINI 7 I-20148 MILAN ITALY OSPED SAN CARLO BARROMEO MILANO,DIV CARDIOL I-20148 MILAN ITALY
Titolo Testata:
Journal of applied physiology
fascicolo: 6, volume: 83, anno: 1997,
pagine: 2123 - 2130
SICI:
8750-7587(1997)83:6<2123:MOPAII>2.0.ZU;2-I
Fonte:
ISI
Lingua:
ENG
Soggetto:
HEMODYNAMICS; RESPIRATION;
Keywords:
PULMONARY CIRCULATION; PULMONARY BLOOD PRESSURE; PULMONARY BLOOD FLOW; INTRAPLEURAL PRESSURE;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
14
Recensione:
Indirizzi per estratti:
Citazione:
P. Castiglioni et al., "MODULATION OF PULMONARY ARTERIAL INPUT IMPEDANCE DURING TRANSITION FROM INSPIRATION TO EXPIRATION", Journal of applied physiology, 83(6), 1997, pp. 2123-2130

Abstract

We investigated whether respiration influences pulmonary arterial input impedance during transition from inspiration to expiration in five anesthetized, spontaneously breathing dogs. Impedance (Z) was separately assessed for heart beats occurring in inspiration, in expiration, and during the transition from inspiration to expiration (transitional beat). Transitional beats were scored by the ratio between the fraction of beat falling in expiration and the total beat duration [expiratory fraction (E-fr)] to quantify their position within the transition. In transitional beats, input resistance linearly increased with Es; Z modulus at the heart-rate frequency (f(HR)) decreased up to -50% for E-fr = 50%. Z phase at f(HR) was greater than in inspiration for E-fr <40% and lower for E-fr > 50%. Unlike blood flow velocity, mean value and first harmonic of pulmonary arterial pressure were correlated to E-fr and paralleled the changes of input resistance and Z at f(HR). This indicates that respiration influences Z through modifications in arterial pressure. The evidence of important respiratory influences on Z function may help the pathophysiological interpretation of dysfunctions of the right heart pumping action, such as the so-called cor pulmonale.

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Documento generato il 30/11/20 alle ore 09:15:09